Detailed information NTG0507898

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: I3K80_RS11725
• Genome accession: NZ_CP065194
• Coordinates: 2349455..2350342 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GDC6P096P
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2344455..2355342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I3K80_RS11695 (I3K80_11695)	-	2344464..2344556 (+)	93	WP_031774855.1	hypothetical protein	-
I3K80_RS11700 (I3K80_11700)	-	2344664..2345161 (-)	498	WP_001065267.1	glutathione peroxidase	-
I3K80_RS11705 (I3K80_11705)	-	2345171..2345431 (-)	261	WP_014937088.1	hypothetical protein	-
I3K80_RS11710 (I3K80_11710)	-	2345813..2345926 (-)	114	WP_014937089.1	hypothetical protein	-
I3K80_RS11715 (I3K80_11715)	-	2346595..2348595 (-)	2001	WP_000776741.1	ABC transporter permease	-
I3K80_RS11720 (I3K80_11720)	-	2348592..2349347 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
I3K80_RS11725 (I3K80_11725)	braS	2349455..2350342 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
I3K80_RS11730 (I3K80_11730)	braR	2350353..2351018 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
I3K80_RS11735 (I3K80_11735)	-	2351044..2351244 (-)	201	WP_000604731.1	hypothetical protein	-
I3K80_RS11740 (I3K80_11740)	-	2351442..2352866 (+)	1425	WP_000953736.1	alkaline phosphatase	-
I3K80_RS14480	-	2352926..2353027 (-)	102	WP_000731972.1	SE2200 family small protein	-
I3K80_RS11750 (I3K80_11750)	-	2353149..2353604 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
I3K80_RS11755 (I3K80_11755)	-	2353848..2354609 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=507898 I3K80_RS11725 WP_000143420.1 2349455..2350342(-) (braS) [Staphylococcus aureus strain GDC6P096P]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=507898 I3K80_RS11725 WP_000143420.1 2349455..2350342(-) (braS) [Staphylococcus aureus strain GDC6P096P]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993