Detailed information NTG0507893

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I3K80_RS08230
• Genome accession: NZ_CP065194
• Coordinates: 1655501..1656544 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GDC6P096P
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1650501..1661544

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I3K80_RS08200 (I3K80_08200)	-	1650922..1652178 (-)	1257	WP_074347694.1	aminopeptidase	-
I3K80_RS08205 (I3K80_08205)	-	1652181..1652381 (-)	201	WP_000180460.1	DUF1128 family protein	-
I3K80_RS08210 (I3K80_08210)	-	1652528..1652992 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
I3K80_RS08215 (I3K80_08215)	-	1652999..1653274 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
I3K80_RS08220 (I3K80_08220)	-	1653552..1654769 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
I3K80_RS08225 (I3K80_08225)	vraR	1654882..1655511 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
I3K80_RS08230 (I3K80_08230)	vraS	1655501..1656544 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
I3K80_RS08235 (I3K80_08235)	liaF	1656541..1657242 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
I3K80_RS08240 (I3K80_08240)	-	1657257..1657643 (-)	387	WP_001110182.1	hypothetical protein	-
I3K80_RS08245 (I3K80_08245)	map	1657860..1658618 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
I3K80_RS08250 (I3K80_08250)	-	1659202..1660188 (+)	987	WP_000999712.1	FUSC family protein	-
I3K80_RS08255 (I3K80_08255)	-	1660377..1660790 (-)	414	WP_025174370.1	hypothetical protein	-
I3K80_RS08260 (I3K80_08260)	-	1660819..1660929 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=507893 I3K80_RS08230 WP_001017131.1 1655501..1656544(-) (vraS) [Staphylococcus aureus strain GDC6P096P]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=507893 I3K80_RS08230 WP_001017131.1 1655501..1656544(-) (vraS) [Staphylococcus aureus strain GDC6P096P]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1