Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   I2438_RS07895 Genome accession   NZ_CP065190
Coordinates   1627210..1629366 (+) Length   718 a.a.
NCBI ID   WP_021321059.1    Uniprot ID   A0AAW3GKX6
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ36     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1622210..1634366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2438_RS07860 (HCFMJIKG_01561) - 1623093..1623296 (-) 204 WP_012516109.1 Blp family class II bacteriocin -
  I2438_RS07865 (HCFMJIKG_01562) - 1623313..1623567 (-) 255 WP_012516110.1 Blp family class II bacteriocin -
  I2438_RS07870 (HCFMJIKG_01563) - 1623721..1624017 (-) 297 WP_021321056.1 bacteriocin immunity protein -
  I2438_RS07875 (HCFMJIKG_01564) - 1624017..1624235 (-) 219 WP_021321057.1 leucocin A/sakacin P family class II bacteriocin -
  I2438_RS07880 - 1624546..1625894 (+) 1349 WP_159334928.1 IS3 family transposase -
  I2438_RS07885 (HCFMJIKG_01567) - 1626400..1626696 (-) 297 WP_012516113.1 bacteriocin immunity protein -
  I2438_RS07890 (HCFMJIKG_01568) - 1626703..1626951 (-) 249 WP_012677516.1 garvicin Q family class II bacteriocin -
  I2438_RS07895 (HCFMJIKG_01569) comA/nlmT 1627210..1629366 (+) 2157 WP_021321059.1 peptide cleavage/export ABC transporter Regulator
  I2438_RS07900 (HCFMJIKG_01570) - 1629377..1630735 (+) 1359 WP_021321060.1 bacteriocin secretion accessory protein -
  I2438_RS07905 (HCFMJIKG_01571) - 1630835..1630969 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I2438_RS10540 (HCFMJIKG_01572) - 1631088..1632422 (-) 1335 WP_021321061.1 sensor histidine kinase -
  I2438_RS07915 (HCFMJIKG_01573) comE/blpR 1632422..1633171 (-) 750 WP_024273220.1 LytR/AlgR family response regulator transcription factor Regulator
  I2438_RS07920 (HCFMJIKG_01574) - 1633798..1634001 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  I2438_RS07925 (HCFMJIKG_01575) - 1634018..1634275 (-) 258 WP_012516121.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80655.79 Da        Isoelectric Point: 7.4614

>NTDB_id=507777 I2438_RS07895 WP_021321059.1 1627210..1629366(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPYKDQKNGLLGFFP
LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAILSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=507777 I2438_RS07895 WP_021321059.1 1627210..1629366(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCCTCGATCGC
AAGGTATTACGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCTCTTG
GTATTGTCATGGCTGCTAAGGAAATGGGGTTTGAAACCAGACCTATCCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCAGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCATATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAACCCTTATATTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTGCTGGTTC
ATACTATCTCCAGGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATCCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCTATCCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTCGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATTGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAATAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAACGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGATTGTTGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-439)

ABC transporter (ABC_tran)

(501-650)

Peptidase C39 family (Peptidase_C39)

(8-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.432

99.861

0.703
  comA Streptococcus mitis SK321

67.321

99.304

0.669
  comA Streptococcus mitis NCTC 12261

67.041

99.304

0.666
  comA Streptococcus pneumoniae Rx1

66.62

99.304

0.662
  comA Streptococcus pneumoniae D39

66.62

99.304

0.662
  comA Streptococcus pneumoniae R6

66.62

99.304

0.662
  comA Streptococcus pneumoniae TIGR4

66.339

99.304

0.659
  comA Streptococcus gordonii str. Challis substr. CH1

65.077

99.304

0.646