Detailed information NTG0507758

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I2438_RS03595
• Genome accession: NZ_CP065190
• Coordinates: 698977..701232 (-)
• Length: 751 a.a.
• NCBI ID: WP_021320502.1
• Uniprot ID: A0AAW3GNG9
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ36
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 693977..706232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2438_RS03580 (HCFMJIKG_00705)	ileS	694752..697550 (+)	2799	WP_021320500.1	isoleucine--tRNA ligase	-
I2438_RS03585 (HCFMJIKG_00706)	-	698020..698322 (-)	303	WP_012515246.1	DUF1827 family protein	-
I2438_RS03590 (HCFMJIKG_00707)	-	698384..698830 (-)	447	WP_021320501.1	NUDIX hydrolase	-
I2438_RS03595 (HCFMJIKG_00708)	clpE	698977..701232 (-)	2256	WP_021320502.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2438_RS03600 (HCFMJIKG_00709)	-	701513..701743 (+)	231	WP_012515249.1	DUF1797 family protein	-
I2438_RS03605 (HCFMJIKG_00710)	-	702188..703255 (-)	1068	WP_337972325.1	LPXTG cell wall anchor domain-containing protein	-
I2438_RS03610 (HCFMJIKG_00711)	-	703601..704284 (+)	684	WP_165626501.1	amino acid ABC transporter permease	-
I2438_RS03615 (HCFMJIKG_00712)	-	704286..705023 (+)	738	WP_230923392.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83849.22 Da
• Isoelectric Point: 5.6718

>NTDB_id=507758 I2438_RS03595 WP_021320502.1 698977..701232(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDTPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=507758 I2438_RS03595 WP_021320502.1 698977..701232(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGCTCTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGACCCGG
TCATCGGACGAGATGATGAGATTATCCGCGTCATCGAAATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAGGAAATCCGCAAGCGCCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTGGGAGCCGGG
GCAGTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
CACCACTCTCAATGAATACCGCATTATCGAAAAGGACGCAGCCCTCGAACGACGCATGCAGCCGGTTAAGGTAGATGAGC
CCTCGGTTGAAGAAACAATCACGATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCTGCTAACCTCTCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTGCT
AGATGAAGCCGGCTCAAAGATGAACCTAACCCTTAACTTTGTTGACCCCAAAGACATTGATAAGCGTTTGATTGAGGCTG
AAAACCTCAAGACACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTATTTCCGCGATCAAATCGCCAAATATAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATACTCCAATCATTACCGATAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGACGCCGTTGATAAAATTGCTAAGGCTATCCGTCGTAATCGTGTTGGACTTGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGACCAACCGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCACGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCCGGCTACGTCGGCTACGAGGAGGCAGGTCAGTTAACGGAGCAGGTGCGCCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATCGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGACGATTAACCGACGGACA
AGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAGGCCTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAACTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGCCCCGAGTTCATGAAT
CGCTTTGATGGCATTATTGAGTTTCAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAACCACCGCCTTGCTCACAATAACATTCGCCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGATGCCATTACCGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (295-392)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.367	98.802	0.834
clpE	Streptococcus pneumoniae Rx1	82.626	100	0.83
clpE	Streptococcus pneumoniae D39	82.626	100	0.83
clpE	Streptococcus pneumoniae R6	82.626	100	0.83
clpE	Streptococcus pneumoniae TIGR4	82.493	100	0.828
clpC	Lactococcus lactis subsp. cremoris KW2	75.532	100	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	90.146	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.885	85.486	0.401
clpC	Streptococcus pneumoniae Rx1	48.214	82.024	0.395
clpC	Streptococcus pneumoniae D39	48.214	82.024	0.395
clpC	Streptococcus pneumoniae TIGR4	48.052	82.024	0.394
clpC	Streptococcus mutans UA159	47.343	82.69	0.391
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus thermophilus LMG 18311	46.338	83.622	0.387