Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SMULJ23_RS03700 Genome accession   NC_017768
Coordinates   759140..760033 (-) Length   297 a.a.
NCBI ID   WP_002276322.1    Uniprot ID   -
Organism   Streptococcus mutans LJ23     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 754140..765033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS03675 (SMULJ23_0702) cas1 755732..756598 (+) 867 WP_014677910.1 type II CRISPR-associated endonuclease Cas1 -
  SMULJ23_RS03680 (SMULJ23_0703) cas2 756595..756939 (+) 345 WP_044560427.1 CRISPR-associated endonuclease Cas2 -
  SMULJ23_RS03685 (SMULJ23_0704) csn2 756929..757591 (+) 663 WP_002263546.1 type II-A CRISPR-associated protein Csn2 -
  SMULJ23_RS03690 (SMULJ23_0705) - 757688..757879 (+) 192 WP_002265423.1 type II toxin-antitoxin system HicA family toxin -
  SMULJ23_RS03695 (SMULJ23_0706) - 757897..758274 (+) 378 WP_002264915.1 type II toxin-antitoxin system HicB family antitoxin -
  SMULJ23_RS03700 (SMULJ23_0707) irvR 759140..760033 (-) 894 WP_002276322.1 XRE family transcriptional regulator Regulator
  SMULJ23_RS03705 (SMULJ23_0708) - 760348..760632 (+) 285 WP_044560428.1 helix-turn-helix transcriptional regulator -
  SMULJ23_RS03710 (SMULJ23_0709) - 760795..762546 (+) 1752 WP_014677913.1 GbpC/Spa domain-containing protein -
  SMULJ23_RS10730 - 762676..762906 (+) 231 WP_024785049.1 hypothetical protein -
  SMULJ23_RS10810 (SMULJ23_0710) - 762941..763069 (+) 129 WP_002262718.1 hypothetical protein -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33657.59 Da        Isoelectric Point: 8.0886

>NTDB_id=50756 SMULJ23_RS03700 WP_002276322.1 759140..760033(-) (irvR) [Streptococcus mutans LJ23]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQKETVTIAADDKTSENTITSKSHHAEYQKIVDSYIAKELKDQTI
IHWDNVIKAKDLYQTLGRQHENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=50756 SMULJ23_RS03700 WP_002276322.1 759140..760033(-) (irvR) [Streptococcus mutans LJ23]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCGATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCTACTATCCTTAACATTCCTACAAGTAGTCTTAACGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTTTACAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAAGAACAAAAAGAAACTGTGACCATAGCTGCTGACGATAAAACATCTGAAAATACGA
TTACCAGCAAATCTCATCATGCAGAATATCAAAAGATTGTCGACTCTTATATCGCCAAAGAGTTAAAAGATCAAACCATT
ATTCATTGGGACAATGTGATAAAAGCTAAAGATCTGTATCAAACCTTAGGACGTCAACACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTACTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(184-296)

Helix-turn-helix (HTH_3)

(22-70)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

92.593

100

0.926

Multiple sequence alignment