Detailed information NTG0507221

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: IRJ20_RS06915
• Genome accession: NZ_CP065137
• Coordinates: 1356175..1357338 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. A1(2020)
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1351175..1362338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IRJ20_RS06885	-	1351440..1351859 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
IRJ20_RS06890	comFC	1351933..1352622 (-)	690	WP_199776864.1	phosphoribosyltransferase family protein	Machinery gene
IRJ20_RS06895	-	1352628..1352912 (-)	285	WP_003151389.1	competence protein ComFB	-
IRJ20_RS06900	comFA	1352970..1354355 (-)	1386	WP_040238815.1	DEAD/DEAH box helicase	Machinery gene
IRJ20_RS06905	-	1354463..1355311 (-)	849	WP_015418336.1	DegV family protein	-
IRJ20_RS06910	degU	1355409..1356098 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
IRJ20_RS06915	degS	1356175..1357338 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
IRJ20_RS06920	-	1357561..1358208 (+)	648	WP_003151384.1	YigZ family protein	-
IRJ20_RS06925	-	1358213..1359427 (+)	1215	WP_033575220.1	LCP family protein	-
IRJ20_RS06930	-	1359517..1360593 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
IRJ20_RS06935	-	1360726..1361922 (-)	1197	WP_015418338.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=507221 IRJ20_RS06915 WP_007407484.1 1356175..1357338(-) (degS) [Bacillus sp. A1(2020)]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=507221 IRJ20_RS06915 WP_007407484.1 1356175..1357338(-) (degS) [Bacillus sp. A1(2020)]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951