Detailed information NTG0050701

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAEMRSA15_RS13940
• Genome accession: NC_017763
• Coordinates: 2731876..2732763 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus subsp. aureus HO 5096 0412
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2726876..2737763

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAEMRSA15_RS13905	-	2726894..2726982 (+)	89	Protein_2649	hypothetical protein	-
SAEMRSA15_RS13910 (SAEMRSA15_25250)	-	2727090..2727587 (-)	498	WP_001065267.1	glutathione peroxidase	-
SAEMRSA15_RS13915	-	2727597..2727857 (-)	261	WP_072434822.1	hypothetical protein	-
SAEMRSA15_RS13920	-	2728239..2728352 (-)	114	WP_072384844.1	hypothetical protein	-
SAEMRSA15_RS13930 (SAEMRSA15_25260)	-	2729016..2731016 (-)	2001	WP_000776746.1	ABC transporter permease	-
SAEMRSA15_RS13935 (SAEMRSA15_25270)	-	2731013..2731768 (-)	756	WP_000923771.1	ABC transporter ATP-binding protein	-
SAEMRSA15_RS13940 (SAEMRSA15_25280)	braS	2731876..2732763 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAEMRSA15_RS13945 (SAEMRSA15_25290)	braR	2732774..2733439 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAEMRSA15_RS13950 (SAEMRSA15_25300)	-	2733465..2733665 (-)	201	WP_000604723.1	hypothetical protein	-
SAEMRSA15_RS13960 (SAEMRSA15_25310)	-	2733863..2735287 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SAEMRSA15_RS15570 (SAEMRSA15_25320)	-	2735347..2735448 (-)	102	WP_000731972.1	SE2200 family small protein	-
SAEMRSA15_RS13965 (SAEMRSA15_25330)	-	2735570..2736025 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAEMRSA15_RS13970 (SAEMRSA15_25340)	-	2736271..2737032 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=50701 SAEMRSA15_RS13940 WP_000143420.1 2731876..2732763(-) (braS) [Staphylococcus aureus subsp. aureus HO 5096 0412]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=50701 SAEMRSA15_RS13940 WP_000143420.1 2731876..2732763(-) (braS) [Staphylococcus aureus subsp. aureus HO 5096 0412]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993