Detailed information NTG0050699

Bioinformatically predicted

Overview

• Name: comGH
• Type: Machinery gene
• Locus tag: SANR_RS01200
• Genome accession: NC_022239
• Coordinates: 218173..219126 (+)
• Length: 317 a.a.
• NCBI ID: WP_003035359.1
• Uniprot ID: I0SGR4
• Organism: Streptococcus anginosus C238
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 213173..224126

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS01160 (SANR_0223)	-	214053..214418 (+)	366	WP_020999445.1	DUF1033 family protein	-
SANR_RS01165 (SANR_0224)	comGA	214488..215429 (+)	942	WP_003033431.1	competence type IV pilus ATPase ComGA	Machinery gene
SANR_RS01170 (SANR_0225)	comGB	215371..216393 (+)	1023	WP_020999446.1	competence type IV pilus assembly protein ComGB	Machinery gene
SANR_RS01175 (SANR_0226)	comGC	216390..216707 (+)	318	WP_020998068.1	competence type IV pilus major pilin ComGC	Machinery gene
SANR_RS01180 (SANR_0227)	comGD	216667..217095 (+)	429	WP_020999411.1	competence type IV pilus minor pilin ComGD	Machinery gene
SANR_RS01185	comGE/cglE	217067..217360 (+)	294	WP_003035318.1	competence type IV pilus minor pilin ComGE	Machinery gene
SANR_RS01190 (SANR_0228)	comGF/cglF	217344..217781 (+)	438	WP_003035329.1	competence type IV pilus minor pilin ComGF	Machinery gene
SANR_RS01195 (SANR_0229)	comGG/cglG	217762..218088 (+)	327	WP_020999447.1	competence type IV pilus minor pilin ComGG	Machinery gene
SANR_RS01200 (SANR_0230)	comGH	218173..219126 (+)	954	WP_003035359.1	class I SAM-dependent methyltransferase	Machinery gene
SANR_RS01205 (SANR_0231)	-	219173..220372 (+)	1200	WP_003035323.1	acetate kinase	-
SANR_RS01210 (SANR_0232)	glmS	220762..222576 (+)	1815	WP_020999448.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
SANR_RS01215 (SANR_0234)	-	222957..223892 (-)	936	WP_020999450.1	IS30 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36018.86 Da
• Isoelectric Point: 4.3141

>NTDB_id=50699 SANR_RS01200 WP_003035359.1 218173..219126(+) (comGH) [Streptococcus anginosus C238]
MNFEKIEQAYSLLLENVQELQNTLLTNFYDALVEQNGVYLDGNTELAIVKKNNETLKSLKLDKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDNIATRYEVASRQEHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKTWLQKHAQIVAMIALPEALFGNAAYAKTIFVLQKQEEQAVQLFVYALSDLRDQDDLLEFSEKFQNWSRESEI

Nucleotide

• Length: 954 bp

>NTDB_id=50699 SANR_RS01200 WP_003035359.1 218173..219126(+) (comGH) [Streptococcus anginosus C238]
ATGAATTTTGAAAAAATAGAACAGGCTTATTCGCTTTTGTTAGAAAATGTCCAGGAGCTCCAAAATACTCTTTTGACGAA
TTTTTATGATGCTTTGGTCGAGCAAAATGGGGTTTATCTGGATGGAAATACAGAGCTAGCTATTGTCAAAAAAAATAATG
AAACACTTAAATCTTTGAAATTAGATAAAGAAGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCTGAGACGATTCTCAATAATACACAAAAAA
ATGTGGATTATCTAGGACTGGAATTGGACGATCTGCTAATTGATATATCAGCCAGTATCGCAGATGTGATGGATGCAAAA
GTTAGTTTTGTGCAAGGTGATGCAGTGCGTCCGCAAGTATTGAAAGAAAGCGATGTGATTATCAGTGATTTACCAGTTGG
CTTTTATCCTGATGATAACATTGCGACGCGCTATGAAGTGGCTAGTAGACAGGAGCATACTTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTGCTGAAAACTTGGCTGCAAAAGCATGCCCAGATAGTTGCGATGATTGCATTGCCAGAAGCACTTTTTGGAAA
TGCCGCTTATGCCAAGACAATTTTTGTGCTGCAAAAGCAAGAAGAACAAGCTGTTCAACTGTTTGTTTATGCTTTGTCTG
ATTTGCGAGATCAGGACGATTTATTGGAATTTAGCGAAAAGTTTCAAAATTGGAGCAGAGAAAGTGAAATTTAA

Domains

Predicted by InterProScan.

• N-6 DNA Methylase (N6_Mtase) (68-299)

3D structure

• AlphaFold DB: I0SGR4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGH	Streptococcus mutans UA140	60.952	99.369	0.606
comGH	Streptococcus mutans UA159	60.635	99.369	0.603