Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   VB13_RS05325 Genome accession   NZ_CP077685
Coordinates   1077370..1078032 (-) Length   220 a.a.
NCBI ID   WP_012560803.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M49 591     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1072370..1083032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS05300 (VB13_05470) - 1072711..1072959 (-) 249 WP_009881160.1 hypothetical protein -
  VB13_RS05305 (VB13_05475) - 1072944..1073171 (-) 228 WP_011054657.1 hypothetical protein -
  VB13_RS05310 (VB13_05480) sodA 1073333..1073938 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  VB13_RS05315 (VB13_05485) holA 1074035..1075075 (-) 1041 WP_011054659.1 DNA polymerase III subunit delta -
  VB13_RS05320 (VB13_05490) comEC/celB 1075146..1077389 (-) 2244 WP_009880877.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  VB13_RS05325 (VB13_05495) comEA/celA/cilE 1077370..1078032 (-) 663 WP_012560803.1 ComEA family DNA-binding protein Machinery gene
  VB13_RS05330 (VB13_05500) - 1078232..1078972 (-) 741 WP_012560804.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  VB13_RS05335 (VB13_05505) - 1079090..1079866 (+) 777 WP_079891413.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  VB13_RS05340 (VB13_05510) - 1079856..1080134 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  VB13_RS05345 (VB13_05515) - 1080158..1082158 (-) 2001 WP_012560805.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24650.47 Da        Isoelectric Point: 6.7451

>NTDB_id=506875 VB13_RS05325 WP_012560803.1 1077370..1078032(-) (comEA/celA/cilE) [Streptococcus pyogenes strain M49 591]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETANKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=506875 VB13_RS05325 WP_012560803.1 1077370..1078032(-) (comEA/celA/cilE) [Streptococcus pyogenes strain M49 591]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAACAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.512

94.091

0.4