Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   VB13_RS03825 Genome accession   NZ_CP077685
Coordinates   752957..753433 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain M49 591     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 747957..758433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS03800 (VB13_03915) - 747998..748786 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  VB13_RS03805 (VB13_03920) - 748826..749932 (+) 1107 WP_032460393.1 FAD-binding oxidoreductase -
  VB13_RS03810 (VB13_03925) rfbA 749990..750859 (+) 870 WP_009880991.1 glucose-1-phosphate thymidylyltransferase RfbA -
  VB13_RS03815 (VB13_03930) - 750859..751452 (+) 594 WP_009880990.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  VB13_RS03820 (VB13_03935) rfbB 751696..752736 (+) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  VB13_RS03825 (VB13_03940) mutX 752957..753433 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  VB13_RS03830 (VB13_03945) - 753491..754672 (+) 1182 WP_009880906.1 AI-2E family transporter -
  VB13_RS03835 (VB13_03950) - 754662..755909 (+) 1248 WP_002990000.1 tetratricopeptide repeat protein -
  VB13_RS03840 (VB13_03955) fbp54 755968..757620 (-) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=506862 VB13_RS03825 WP_002984880.1 752957..753433(+) (mutX) [Streptococcus pyogenes strain M49 591]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=506862 VB13_RS03825 WP_002984880.1 752957..753433(+) (mutX) [Streptococcus pyogenes strain M49 591]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703