Detailed information NTG0506624

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I2437_RS08855
• Genome accession: NZ_CP065061
• Coordinates: 1886028..1888469 (-)
• Length: 813 a.a.
• NCBI ID: WP_206157837.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ33
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1881028..1893469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2437_RS08815 (IEMOCGPF_01759)	groES	1881084..1881371 (-)	288	WP_012514806.1	co-chaperone GroES	-
I2437_RS08820 (IEMOCGPF_01760)	-	1881671..1881961 (-)	291	WP_012514805.1	hypothetical protein	-
I2437_RS08825 (IEMOCGPF_01761)	-	1881942..1882334 (-)	393	WP_165627867.1	hypothetical protein	-
I2437_RS08830 (IEMOCGPF_01762)	-	1882316..1883605 (-)	1290	WP_206158052.1	hypothetical protein	-
I2437_RS08835 (IEMOCGPF_01763)	-	1883607..1884038 (-)	432	WP_165628130.1	hypothetical protein	-
I2437_RS08840 (IEMOCGPF_01765)	-	1884257..1884688 (-)	432	WP_042669845.1	hypothetical protein	-
I2437_RS08845 (IEMOCGPF_01767)	-	1884823..1885251 (-)	429	WP_165628129.1	hypothetical protein	-
I2437_RS09775	-	1885533..1885678 (+)	146	Protein_1694	putative holin-like toxin	-
I2437_RS08855 (IEMOCGPF_01768)	clpC	1886028..1888469 (-)	2442	WP_206157837.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2437_RS08860 (IEMOCGPF_01769)	-	1888469..1888930 (-)	462	WP_012677252.1	CtsR family transcriptional regulator	-
I2437_RS08865 (IEMOCGPF_01770)	-	1889100..1889303 (-)	204	WP_037583955.1	cold-shock protein	-
I2437_RS08875 (IEMOCGPF_01772)	ahpC	1889934..1890494 (+)	561	WP_126436215.1	alkyl hydroperoxide reductase subunit C	-
I2437_RS08880 (IEMOCGPF_01773)	ahpF	1890515..1892047 (+)	1533	WP_165628127.1	alkyl hydroperoxide reductase subunit F	-
I2437_RS08885 (IEMOCGPF_01774)	-	1892097..1893356 (-)	1260	WP_014622678.1	ISL3-like element ISSeq1 family transposase	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90479.36 Da
• Isoelectric Point: 6.5235

>NTDB_id=506624 I2437_RS08855 WP_206157837.1 1886028..1888469(-) (clpC) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MMIYSLKMQDIFNRAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIKAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVIAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMNKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSRLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAIGHDHQTMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAALAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQSLK
IGVSRGKLAFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=506624 I2437_RS08855 WP_206157837.1 1886028..1888469(-) (clpC) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
GTGATGATTTATTCATTAAAGATGCAAGACATTTTTAATCGGGCTCAATTTCAAGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCATATTTTATTAGCTATGGTAGCTGTTGACCATTCCTTAGCGGCCATGGTGTTAAGCGAATTTGAACGAA
AGATTAAGGCCGAAGAGTATGAGGCTGCTGCTATTTTAGCCATGGGAAAAAGTCCCAAAGAGGTGACTTCTGTCCAATTC
AAGCCACAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTTACCAATGAGCATGAGGTTGG
CTCAGAGCATGTGCTCTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTTTGTTAGAGTTGGCAGGCTACAGGC
TCAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGCTAAATGCCGGCTATAGCAAGGAA
ACTATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGAGTAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACAAGAGACCTGACAGAGATGGCAAGACAGGGCTTATTAGAGCCAGTCATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTTTGTCGTAAGACGAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTCGGAAAAACTGCTCTAGCTTATGGCTTAGCGCAGCGAATTGCTAATGGAGCCATTCCTTATGAATTACAAGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGATTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGTAAGATCATTTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACTCTTGATGCAGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGCGCTACAAC
TCAAGAGGAATATCAAAAGCACATTGAAAAGGACGCAGCCCTTTCTCGTCGCTTTGCCAAGATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTGTCCATACAGCTGTGAAGCTGGCTCGGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACGCCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAACAAGGTGTCAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAGGCTATCAGGTATTCCACTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
AAATTTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ATCAGTCAGGCATTCGCACAGGCAGACGCCCGATTGGCTCCTTTATGTTTCTTGGTCCAACCGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCTCGTCTCAATGGTGCTCCTCCTGGCTATGTTGGCTATGATGAAGGAGGCGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTCGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCGGTCATGACCATCAAACAATGGAAA
AGCGTATTTTGGAGGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAGAAGGTGGTCTTCCATAGC
CTAACACAGGAAAACATGCGTGATGTGGTGAAAATTATGGTTAAGCCGCTGATTGCAGCCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTATCTGAAGCTGGTTACGATGTTGAAATGGGCGCTCGCCCACTTCGTC
GCACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGAGTTATCAAGTGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGCTAGCTTTTGATATCGCTTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (374-459)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-51)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-131)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.416	100	0.744
clpC	Streptococcus thermophilus LMD-9	72.304	100	0.726
clpC	Streptococcus thermophilus LMG 18311	72.059	100	0.723
clpC	Streptococcus pneumoniae Rx1	65.848	100	0.659
clpC	Streptococcus pneumoniae D39	65.848	100	0.659
clpC	Streptococcus pneumoniae TIGR4	65.725	100	0.658
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.503	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	43.713	100	0.449
clpE	Streptococcus mutans UA159	45.356	79.459	0.36