Detailed information NTG0506614

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I2437_RS06775
• Genome accession: NZ_CP065061
• Coordinates: 1425322..1427577 (+)
• Length: 751 a.a.
• NCBI ID: WP_206157763.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ33
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1420322..1432577

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2437_RS06755 (IEMOCGPF_01348)	-	1421698..1422435 (-)	738	WP_021320504.1	ATP-binding cassette domain-containing protein	-
I2437_RS06760 (IEMOCGPF_01349)	-	1422437..1423120 (-)	684	WP_206157761.1	amino acid ABC transporter permease	-
I2437_RS06765 (IEMOCGPF_01350)	-	1423509..1424366 (+)	858	WP_206157762.1	LPXTG cell wall anchor domain-containing protein	-
I2437_RS06770 (IEMOCGPF_01351)	-	1424809..1425039 (-)	231	WP_012515249.1	DUF1797 family protein	-
I2437_RS06775 (IEMOCGPF_01352)	clpE	1425322..1427577 (+)	2256	WP_206157763.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2437_RS06780 (IEMOCGPF_01353)	-	1427724..1428170 (+)	447	WP_043025456.1	NUDIX hydrolase	-
I2437_RS06785 (IEMOCGPF_01354)	-	1428232..1428534 (+)	303	WP_012515246.1	DUF1827 family protein	-
I2437_RS06790 (IEMOCGPF_01355)	ileS	1429004..1431802 (-)	2799	WP_165627681.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83839.18 Da
• Isoelectric Point: 5.6718

>NTDB_id=506614 I2437_RS06775 WP_206157763.1 1425322..1427577(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNSFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDTPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=506614 I2437_RS06775 WP_206157763.1 1425322..1427577(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGTATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACTCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGACCCGG
TCATCGGACGAGATGATGAGATTATCCGCGTCATCGAAATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAGGAAATCCGCAAGCGCCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTGGGAGCCGGG
GCAGTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
CACCACTCTCAATGAATACCGCATTATCGAAAAGGACGCAGCCCTCGAACGACGCATGCAGCCGGTTAAGGTAGATGAGC
CCTCGGTTGAAGAAACAATCACGATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCCGCCAACCTATCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTACT
AGATGAGGCTGGCTCAAAAATGAACCTAACCCTTAACTTTGTTGACCCAAAAGACATCGACAAGCGTTTGATTGAGGCTG
AAAACCTCAAGACACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTACTTCCGCGATCAAATCGCCAAATACAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATACTCCAATCATTACCGATAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGACGCCGTTGATAAAATTGCTAAGGCTATCCGTCGTAATCGTGTTGGACTTGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGACCAACCGGTGTCGGAAAAACAGAGCTTTCCAAGCAATTAGCTATTGAGCTTTT
TGGCTCTGCTGATAATATGATTCGCTTTGACATGTCTGAATATATGGAAAAGCATGCTGTGGCTAAGCTTGTAGGTGCCC
CTCCAGGCTACGTTGGCTATGAGGAGGCAGGGCAGTTAACAGAGCAGGTACGCCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATTGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGTCGATTAACCGACGGACA
GGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAGGCCTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAACTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGCCCCGAGTTCATGAAT
CGCTTTGATGGCATTATTGAGTTTCAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAACCACCGCCTTGCTCACAATAACATTCGCCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGATGCCATTACCGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (295-392)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.232	98.802	0.832
clpE	Streptococcus pneumoniae Rx1	82.626	100	0.83
clpE	Streptococcus pneumoniae D39	82.626	100	0.83
clpE	Streptococcus pneumoniae R6	82.626	100	0.83
clpE	Streptococcus pneumoniae TIGR4	82.493	100	0.828
clpC	Lactococcus lactis subsp. cremoris KW2	75.432	100	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	90.146	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.885	85.486	0.401
clpC	Streptococcus pneumoniae Rx1	48.214	82.024	0.395
clpC	Streptococcus pneumoniae D39	48.214	82.024	0.395
clpC	Streptococcus pneumoniae TIGR4	48.052	82.024	0.394
clpC	Streptococcus mutans UA159	47.343	82.69	0.391
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus thermophilus LMG 18311	46.338	83.622	0.387