Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I2436_RS08175 Genome accession   NZ_CP065060
Coordinates   1734249..1734935 (-) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1729249..1739935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS08155 (GDAKBCAL_01634) dnaI 1730014..1730922 (-) 909 WP_154803557.1 primosomal protein DnaI -
  I2436_RS08160 (GDAKBCAL_01635) - 1730923..1732086 (-) 1164 WP_173302778.1 helicase loader -
  I2436_RS08165 (GDAKBCAL_01636) nrdR 1732070..1732564 (-) 495 WP_012516251.1 transcriptional regulator NrdR -
  I2436_RS08170 (GDAKBCAL_01637) - 1732755..1734245 (-) 1491 WP_206152789.1 HAMP domain-containing histidine kinase -
  I2436_RS08175 (GDAKBCAL_01638) covR 1734249..1734935 (-) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  I2436_RS08180 (GDAKBCAL_01639) - 1735121..1735654 (-) 534 WP_012516254.1 DUF177 domain-containing protein -
  I2436_RS08185 (GDAKBCAL_01640) htpX 1735942..1736835 (-) 894 WP_012516255.1 zinc metalloprotease HtpX -
  I2436_RS08190 (GDAKBCAL_01641) - 1736867..1737424 (-) 558 WP_012677410.1 LemA family protein -
  I2436_RS08195 (GDAKBCAL_01642) rsmG 1737560..1738273 (+) 714 WP_012516257.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=506562 I2436_RS08175 WP_012516253.1 1734249..1734935(-) (covR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=506562 I2436_RS08175 WP_012516253.1 1734249..1734935(-) (covR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCGCTTGAGCTACAACATGAGGGTTA
CGAGGTGACCGTCGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGATTTGAAGTGACACGTCGATTGCAAACAGAAAAAACGACTTACATCATGATGATGACT
GCGCGTGACTCTATTATGGACGTTGTAGCTGGCTTGGATCGTGGTGCTGACGATTACATCGTGAAGCCATTTGCCATTGA
GGAATTGCTGGCGCGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAAACTAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATCGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425