Detailed information NTG0506535

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I2436_RS02955
• Genome accession: NZ_CP065060
• Coordinates: 604177..606432 (-)
• Length: 751 a.a.
• NCBI ID: WP_206153039.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ28
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 599177..611432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2436_RS02940 (GDAKBCAL_00587)	ileS	599951..602749 (+)	2799	WP_206153037.1	isoleucine--tRNA ligase	-
I2436_RS02945 (GDAKBCAL_00588)	-	603220..603522 (-)	303	WP_012515246.1	DUF1827 family protein	-
I2436_RS02950 (GDAKBCAL_00589)	-	603584..604030 (-)	447	WP_012515247.1	NUDIX hydrolase	-
I2436_RS02955 (GDAKBCAL_00590)	clpE	604177..606432 (-)	2256	WP_206153039.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2436_RS02960 (GDAKBCAL_00591)	-	606715..606945 (+)	231	WP_012515249.1	DUF1797 family protein	-
I2436_RS02965 (GDAKBCAL_00592)	-	607390..608355 (-)	966	WP_206153041.1	LPXTG cell wall anchor domain-containing protein	-
I2436_RS02970 (GDAKBCAL_00593)	-	608701..609384 (+)	684	WP_206153043.1	amino acid ABC transporter permease	-
I2436_RS02975 (GDAKBCAL_00594)	-	609386..610123 (+)	738	WP_111692290.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83817.22 Da
• Isoelectric Point: 5.6718

>NTDB_id=506535 I2436_RS02955 WP_206153039.1 604177..606432(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLVEAENLKAQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=506535 I2436_RS02955 WP_206153039.1 604177..606432(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCCAAGCGCGGTGATATTGATCCTG
TCATCGGACGTGACGATGAGATTATCCGCGTGATCGAAATTCTCAATCGCCGAACGAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATTGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAAGAAATCCGCAAGCGCCATGACGTGATTCTATTTATTGATGAAATCCATGAAATTGTGGGAGCTGGT
GCAGTTGGTGACGGCAGCATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
GACCACTCTCAATGAATACCGCATCATCGAAAAGGACGCAGCCCTTGAGCGACGCATGCAGCCGGTTAAGGTGGATGAGC
CTTCGGTTGAAGAAACAATCACGATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCCGCCAACCTATCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTACT
AGATGAGGCTGGCTCAAAAATGAACCTAACCCTTAACTTTGTTGACCCAAAAGACATCGACAAGCGTTTGGTTGAGGCAG
AAAACCTTAAGGCACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTACTTCCGCGATCAAATCGCCAAATACAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATATTCCAATCATCACTGACAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGACGCCGTTGATAAAATTGCTAAGGCTATCCGTCGTAATCGTGTTGGACTTGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGACCAACCGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCACGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCCGGCTACGTCGGCTACGAGGAGGCAGGTCAGTTAACGGAGCAGGTGCGCCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATCGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGACGATTAACCGACGGACA
AGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAGGCCTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAACTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGCCCCGAGTTCATGAAT
CGCTTTGATGGCATTATTGAGTTTCAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAACCACCGCCTTGCTCACAATAACATTCGCCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGATGCCATTACCGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• AAA lid domain (AAA_lid_9) (295-392)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.232	98.802	0.832
clpE	Streptococcus pneumoniae Rx1	82.361	100	0.827
clpE	Streptococcus pneumoniae D39	82.361	100	0.827
clpE	Streptococcus pneumoniae R6	82.361	100	0.827
clpE	Streptococcus pneumoniae TIGR4	82.228	100	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	75.532	100	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	90.146	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.885	85.486	0.401
clpC	Streptococcus pneumoniae Rx1	48.214	82.024	0.395
clpC	Streptococcus pneumoniae D39	48.214	82.024	0.395
clpC	Streptococcus pneumoniae TIGR4	48.052	82.024	0.394
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus mutans UA159	47.182	82.69	0.39
clpC	Streptococcus thermophilus LMG 18311	46.19	83.888	0.387