Detailed information NTG0506516

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: I2436_RS00280
• Genome accession: NZ_CP065060
• Coordinates: 47868..48782 (+)
• Length: 304 a.a.
• NCBI ID: WP_042669756.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ28
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42868..53782

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2436_RS00260 (GDAKBCAL_00052)	purE	44045..44533 (+)	489	WP_021320238.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
I2436_RS00265 (GDAKBCAL_00053)	purK	44520..45593 (+)	1074	WP_206152857.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
I2436_RS00270 (GDAKBCAL_00054)	-	45608..45832 (+)	225	WP_012677202.1	hypothetical protein	-
I2436_RS00275 (GDAKBCAL_00055)	purB	46277..47569 (+)	1293	WP_206152858.1	adenylosuccinate lyase	-
I2436_RS00280 (GDAKBCAL_00056)	comR	47868..48782 (+)	915	WP_042669756.1	XRE family transcriptional regulator	Regulator
I2436_RS00290 (GDAKBCAL_00058)	ruvB	48997..49998 (+)	1002	WP_042669757.1	Holliday junction branch migration DNA helicase RuvB	-
I2436_RS00295 (GDAKBCAL_00059)	-	50246..50704 (+)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
I2436_RS00300 (GDAKBCAL_00060)	-	50710..51111 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
I2436_RS00305 (GDAKBCAL_00061)	-	51108..52889 (+)	1782	WP_111710078.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35806.34 Da
• Isoelectric Point: 4.5517

>NTDB_id=506516 I2436_RS00280 WP_042669756.1 47868..48782(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=506516 I2436_RS00280 WP_042669756.1 47868..48782(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTTGATATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.498	98.355	0.487
comR	Streptococcus suis D9	37.874	99.013	0.375
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis P1/7	38.644	97.039	0.375