Detailed information NTG0506500

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I2435_RS07270
• Genome accession: NZ_CP065059
• Coordinates: 1483511..1485766 (+)
• Length: 751 a.a.
• NCBI ID: WP_206156356.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ25
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1478511..1490766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2435_RS07250 (JFMEOBDD_01460)	-	1479749..1480486 (-)	738	WP_021320504.1	ATP-binding cassette domain-containing protein	-
I2435_RS07255 (JFMEOBDD_01461)	-	1480488..1481171 (-)	684	WP_206156354.1	amino acid ABC transporter permease	-
I2435_RS07260 (JFMEOBDD_01462)	-	1481516..1482553 (+)	1038	WP_206156355.1	LPXTG cell wall anchor domain-containing protein	-
I2435_RS07265 (JFMEOBDD_01463)	-	1482998..1483228 (-)	231	WP_012515249.1	DUF1797 family protein	-
I2435_RS07270 (JFMEOBDD_01464)	clpE	1483511..1485766 (+)	2256	WP_206156356.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2435_RS07275 (JFMEOBDD_01465)	-	1485914..1486360 (+)	447	WP_206156357.1	NUDIX hydrolase	-
I2435_RS07280 (JFMEOBDD_01466)	-	1486422..1486724 (+)	303	WP_012515246.1	DUF1827 family protein	-
I2435_RS07285 (JFMEOBDD_01467)	ileS	1487382..1490180 (-)	2799	WP_206156358.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83882.29 Da
• Isoelectric Point: 5.4936

>NTDB_id=506500 I2435_RS07270 WP_206156356.1 1483511..1485766(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGTPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLRIVHLMLDDVNQRLAHNSIHLDVTEKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=506500 I2435_RS07270 WP_206156356.1 1483511..1485766(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGACCCGG
TCATCGGACGAGATGATGAGATTATCCGCGTCATCGAAATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAAGAAATCCGCAAGCGCCATGACGTGATTCTATTTATTGATGAAATCCATGAAATTGTGGGAGCTGGT
GCAGTTGGTGACGGCAGCATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
GACCACTCTCAATGAATACCGCATCATCGAAAAGGACGCAGCCCTTGAGCGACGCATGCAGCCGGTTAAGGTGGATGAGC
CTTCGGTTGAAGAAACAATCACTATCCTAAAAGGAATCCAACCCAAATATGAGGACTATCATCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCTGCTAACCTCTCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTGCT
AGATGAAGCCGGCTCAAAGATGAACCTAACCCTTAACTTTGTTGACCCCAAAGACATTGATAAGCGTTTGATTGAGGCTG
AAAACCTCAAGACCCAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTATTTCCGCGATCAAATCGCCAAATATAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAAGATATCCCGATCATCACTGACAAGACCATCGAAGCAATCGTTGAACAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAAGAACAATCACAGCTAGTCAATCTGGCCGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGATGCTGTTGATAAAATTGCAAAGGCTATCCGTCGTAATCGTGTTGGACTGGGAACCCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGCCCAACTGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCATGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCTGGCTACGTCGGCTATGAGGAGGCGGGTCAGTTAACAGAGCAGGTGCGCCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATCGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGTCGATTAACCGACGGACA
GGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAAGCCTCAGTCG
GCTTTGGTGCTGCTAGAGAAGGACGGACAAACTCTGTCCTAGGTGAGCTTAGTCATTTCTTTAGTCCCGAATTTATGAAC
CGCTTTGACGGGATTATTGAGTTTCAGCCGCTAAGCAAGGACAATCTGCTACGTATCGTTCACTTAATGCTTGATGACGT
TAATCAGCGCCTTGCTCACAATAGCATTCACCTTGATGTGACCGAAAAGGTCAAGGAAAAGCTCGTCGAGCTAGGCTATG
ATCCCAAGATGGGAGCACGACCACTGCGCCGCACCATTCAGGATTACATTGAGGACGCTATTACTGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCTTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• AAA lid domain (AAA_lid_9) (295-392)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.771	98.802	0.838
clpE	Streptococcus pneumoniae Rx1	82.361	100	0.827
clpE	Streptococcus pneumoniae D39	82.361	100	0.827
clpE	Streptococcus pneumoniae R6	82.361	100	0.827
clpE	Streptococcus pneumoniae TIGR4	82.228	100	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	75.399	100	0.755
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	90.146	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.885	85.486	0.401
clpC	Streptococcus pneumoniae Rx1	48.052	82.024	0.394
clpC	Streptococcus pneumoniae D39	48.052	82.024	0.394
clpC	Streptococcus pneumoniae TIGR4	47.89	82.024	0.393
clpC	Streptococcus thermophilus LMD-9	46.667	83.888	0.391
clpC	Streptococcus mutans UA159	47.182	82.69	0.39
clpC	Streptococcus thermophilus LMG 18311	46.349	83.888	0.389