Detailed information NTG0506465

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I2435_RS00845
• Genome accession: NZ_CP065059
• Coordinates: 145761..148202 (+)
• Length: 813 a.a.
• NCBI ID: WP_206156538.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ25
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 140761..153202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2435_RS00815 (JFMEOBDD_00163)	ahpF	141101..142633 (-)	1533	WP_042669839.1	alkyl hydroperoxide reductase subunit F	-
I2435_RS00820 (JFMEOBDD_00164)	ahpC	142654..143214 (-)	561	WP_012514798.1	alkyl hydroperoxide reductase subunit C	-
I2435_RS00830 (JFMEOBDD_00166)	-	143896..144546 (+)	651	WP_231196254.1	exotoxin	-
I2435_RS00835 (JFMEOBDD_00167)	-	144925..145128 (+)	204	WP_012514799.1	cold-shock protein	-
I2435_RS00840 (JFMEOBDD_00168)	-	145300..145761 (+)	462	WP_012514800.1	CtsR family transcriptional regulator	-
I2435_RS00845 (JFMEOBDD_00169)	clpC	145761..148202 (+)	2442	WP_206156538.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2435_RS00850 (JFMEOBDD_00170)	-	148553..148699 (-)	147	WP_080312399.1	putative holin-like toxin	-
I2435_RS00855 (JFMEOBDD_00171)	-	148979..149413 (+)	435	WP_043030360.1	hypothetical protein	-
I2435_RS00860 (JFMEOBDD_00173)	-	149535..149966 (+)	432	WP_043030361.1	membrane protein	-
I2435_RS00865 (JFMEOBDD_00175)	-	150195..150608 (+)	414	WP_043052251.1	hypothetical protein	-
I2435_RS00870 (JFMEOBDD_00176)	-	150611..151924 (+)	1314	WP_043052250.1	hypothetical protein	-
I2435_RS00875 (JFMEOBDD_00177)	-	151906..152298 (+)	393	WP_165626285.1	hypothetical protein	-
I2435_RS00880 (JFMEOBDD_00178)	-	152279..152569 (+)	291	WP_021320276.1	hypothetical protein	-
I2435_RS00885 (JFMEOBDD_00179)	groES	152869..153156 (+)	288	WP_012514806.1	co-chaperone GroES	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90432.26 Da
• Isoelectric Point: 6.2961

>NTDB_id=506465 I2435_RS00845 WP_206156538.1 145761..148202(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MMTYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKTKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIASGVIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AIHTAVKLAQRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSRLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAISQDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAVLAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGDLSSGQSLK
IGVSRGKLAFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=506465 I2435_RS00845 WP_206156538.1 145761..148202(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
GTGATGACTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAGGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCACATTTTATTAGCTATGGTAGCTGTTGATCATTCTTTAGCAGCCATGGTTTTAAGCGAATTTGAACGAA
AGATCAGAGCTGAAGAGTATGAGGCAGCTGCTATTTTAGCTATGGGAAAAAGTCCCAAGGAGGTGACTTCTGTCCAATTC
AAGCCGCAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTCACCAATGAGCATGAGGTTGG
CTCAGAGCATGTGCTTTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTCTGTTAGAGTTGGCAGGCTACAGGC
TCAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGTTAAATGCCGGCTATAGTAAGGAA
ACCATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGACGAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACTAGAGACCTGACAGAGATGGCAAGACAGGGCTTGTTAGAGCCAGTTATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTCTGTCGTAAGACTAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTTGGAAAAACTGCTCTAGCTTATGGCTTGGCACAGCGTATTGCAAGCGGCGTGATTCCTTATGAATTACAGGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGTAAGATCATTTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACACTTGATGCCGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGCGCTACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAGGACGCAGCTCTTTCTCGTCGCTTTGCCAAGATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTATCCATACTGCTGTGAAGCTGGCTCAGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACACCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAGCAAGGTGTCAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGTTAAAACCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAGGCTATCAGGTATTCCACTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
AAATTTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ACCAGTCAGGCATTCGCACAGGCAGACGCCCGATTGGCTCCTTTATGTTTCTTGGTCCAACCGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCTCGTCTCAATGGTGCTCCTCCTGGCTATGTTGGCTATGATGAAGGAGGCGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCTGTTCTTCTTTTTGATGAGGTCGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCAGCCAGGACCATCAAGCAATGGAAA
AGCGTATTTTAGAAGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAGAAGGTGGTCTTCCATAGC
CTAACACAGGAAAACATGCGTGATGTGGTGAAAATTATGGTTAAGCCGCTGATTGCAGTCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTATCTGAAGCTGGTTACGATGTTGAAATGGGTGCTCGCCCACTTCGCC
GTACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGATTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGCTAGCTTTTGATATCGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA lid domain (AAA_lid_9) (374-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-131)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-51)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.785	100	0.748
clpC	Streptococcus thermophilus LMD-9	72.059	100	0.723
clpC	Streptococcus thermophilus LMG 18311	71.814	100	0.721
clpC	Streptococcus pneumoniae Rx1	66.093	100	0.662
clpC	Streptococcus pneumoniae D39	66.093	100	0.662
clpC	Streptococcus pneumoniae TIGR4	65.971	100	0.661
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.507	100	0.499
clpC	Bacillus subtilis subsp. subtilis str. 168	43.832	100	0.45