Detailed information NTG0506406

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I2434_RS00890
• Genome accession: NZ_CP065058
• Coordinates: 158966..161407 (+)
• Length: 813 a.a.
• NCBI ID: WP_165623668.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ18
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 153966..166407

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2434_RS00860 (MCPGFBBE_00172)	ahpF	154308..155840 (-)	1533	WP_165623697.1	alkyl hydroperoxide reductase subunit F	-
I2434_RS00865 (MCPGFBBE_00173)	ahpC	155861..156421 (-)	561	WP_126436215.1	alkyl hydroperoxide reductase subunit C	-
I2434_RS00875 (MCPGFBBE_00175)	-	157101..157751 (+)	651	WP_269204273.1	exotoxin beta-grasp domain-containing protein	-
I2434_RS00880 (MCPGFBBE_00176)	-	158130..158333 (+)	204	WP_012514799.1	cold-shock protein	-
I2434_RS00885 (MCPGFBBE_00177)	-	158505..158966 (+)	462	WP_012677252.1	CtsR family transcriptional regulator	-
I2434_RS00890 (MCPGFBBE_00178)	clpC	158966..161407 (+)	2442	WP_165623668.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2434_RS10005	-	161755..161900 (-)	146	Protein_141	putative holin-like toxin	-
I2434_RS00900 (MCPGFBBE_00179)	-	162181..162615 (+)	435	WP_111677663.1	hypothetical protein	-
I2434_RS00905 (MCPGFBBE_00181)	-	162737..163177 (+)	441	WP_111677664.1	hypothetical protein	-
I2434_RS00910 (MCPGFBBE_00183)	-	163396..163809 (+)	414	WP_042669846.1	hypothetical protein	-
I2434_RS00915 (MCPGFBBE_00184)	-	163812..165125 (+)	1314	WP_206157626.1	hypothetical protein	-
I2434_RS00920 (MCPGFBBE_00185)	-	165107..165499 (+)	393	WP_043052249.1	hypothetical protein	-
I2434_RS00925 (MCPGFBBE_00186)	-	165480..165770 (+)	291	WP_206157627.1	hypothetical protein	-
I2434_RS00930 (MCPGFBBE_00187)	groES	166069..166356 (+)	288	WP_012514806.1	co-chaperone GroES	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90498.36 Da
• Isoelectric Point: 6.3877

>NTDB_id=506406 I2434_RS00890 WP_165623668.1 158966..161407(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMNKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSRLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAISQDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAVLAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGDLSSGQSLK
IGVSRGKLVFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=506406 I2434_RS00890 WP_165623668.1 158966..161407(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
GTGATGATTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAAGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCATATTTTATTAGCTATGGTAGCTGTTGACCATTCCTTAGCGGCCATGGTGTTAAGCGAATTTGAACGAA
AGATTAGGGCTGAAGAGTATGAGGCTGCTGCTATTTTAGCCATGGGAAAAAGTCCCAAAGAGGTGACTTCTGTCCAATTC
AAGCCACAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTTACCAATGAGCATGAGGTTGG
CTCAGAGCATGTACTCTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTCTGTTAGAATTGGCAGGCTACAGGC
TCAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGCTAAATGCCGGCTATAGCAAGGAA
ACTATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGAGTAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACAAGAGACCTGACAGAGATGGCAAGACAGGGCTTATTAGAGCCAGTCATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTTTGTCGTAAGACGAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTCGGAAAAACTGCTCTAGCTTATGGCTTAGCGCAGCGAATTGCTAATGGAGCCATTCCTTATGAATTACAAGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGTAAGATCATTTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACTCTTGATGCAGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGCGCTACAAC
TCAAGAGGAATATCAAAAGCACATTGAAAAGGACGCAGCCCTTTCTCGTCGCTTTGCCAAGATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTGTCCATACAGCTGTGAAGCTGGCTCGGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACGCCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAACAAGGTGTCAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAGGCTATCAGGTATTCCACTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
AAATTTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ATCAGTCAGGCATTCGCACAGGCAGACGCCCGATTGGCTCCTTTATGTTTCTTGGTCCAACCGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCTCGTCTCAATGGTGCTCCTCCTGGCTATGTTGGCTATGATGAAGGAGGCGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTCGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCAGCCAGGATCACCAAGCCATGGAAA
AGCGTATTTTAGAGGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAAAAGGTGGTCTTCCACAGC
CTAACACAGGAAAACATGCGTGATGTGGTCAAAATTATGGTTAAGCCGCTGATTGCAGTCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTGTCTGAAGCTGGTTACGATGTTGAAATGGGCGCTCGCCCACTTCGTC
GCACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGATTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGTTAGTTTTTGATATTGCTTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA lid domain (AAA_lid_9) (374-459)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-131)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-51)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	75.031	100	0.75
clpC	Streptococcus thermophilus LMD-9	72.304	100	0.726
clpC	Streptococcus thermophilus LMG 18311	72.059	100	0.723
clpC	Streptococcus pneumoniae Rx1	66.093	100	0.662
clpC	Streptococcus pneumoniae D39	66.093	100	0.662
clpC	Streptococcus pneumoniae TIGR4	65.971	100	0.661
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.623	100	0.499
clpC	Bacillus subtilis subsp. subtilis str. 168	44.019	100	0.453
clpE	Streptococcus mutans UA159	45.356	79.459	0.36