Detailed information NTG0506384

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: I2433_RS07825
• Genome accession: NZ_CP065056
• Coordinates: 1611018..1613171 (-)
• Length: 717 a.a.
• NCBI ID: WP_111677831.1
• Uniprot ID: A0AAX2LHA3
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ14
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1606018..1618171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2433_RS07805 (JDBNIEOD_01569)	nrdI	1607013..1607420 (-)	408	WP_115251472.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
I2433_RS07810 (JDBNIEOD_01570)	nrdF	1607422..1608435 (-)	1014	WP_196819914.1	class 1b ribonucleoside-diphosphate reductase subunit beta	-
I2433_RS07815 (JDBNIEOD_01571)	-	1608891..1609127 (-)	237	WP_196819913.1	hypothetical protein	-
I2433_RS07820 (JDBNIEOD_01572)	comB	1609636..1611003 (-)	1368	WP_012515170.1	bacteriocin secretion accessory protein	Regulator
I2433_RS07825 (JDBNIEOD_01573)	comA	1611018..1613171 (-)	2154	WP_111677831.1	peptide cleavage/export ABC transporter ComA	Regulator
I2433_RS07830 (JDBNIEOD_01574)	-	1613398..1613565 (-)	168	WP_196819912.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I2433_RS07835 (JDBNIEOD_01575)	-	1613588..1613734 (-)	147	WP_021320464.1	hypothetical protein	-
I2433_RS07840 (JDBNIEOD_01576)	-	1613748..1613906 (-)	159	WP_021320463.1	hypothetical protein	-
I2433_RS07845 (JDBNIEOD_01577)	-	1614019..1614159 (-)	141	WP_012515166.1	hypothetical protein	-
I2433_RS07850 (JDBNIEOD_01579)	-	1614512..1615405 (-)	894	WP_196819911.1	XRE family transcriptional regulator	-
I2433_RS07855 (JDBNIEOD_01580)	metG	1615963..1617966 (-)	2004	WP_196819910.1	methionine--tRNA ligase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80467.39 Da
• Isoelectric Point: 9.0606

>NTDB_id=506384 I2433_RS07825 WP_111677831.1 1611018..1613171(-) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MKFRRKHYRAQVDTRDCGVASLAMIYGYYGSYYSLATLREAAKTTQEGTTAFGLVKVSEALGFETRAIRADMSLFDVEGL
SYPFIAHVLKKGKFLHYYVVTGQDKKYIHIADPDPTVKLTCLSRQRFASEWTGVTIFIAPTPEYKPHKEKKNSLLDFVPL
LAKQKGLITNIVVATLLVTIINIIGSYYLQSIIDTYVPSVMKNTLGIISVGLVIVYALQQVISYAQEYLLLILGQRLSID
VILSYIKHIFNLPMSFFATRRTGEIVSRFNDANSIIDALASTILSIFLDVSVIVIISLVLFSQNVNLFVISLLALPIYAV
IIFAFMKPFERMNQETMEANSIMSSSIIEDINGIETIKSLTSEKIRYQKIDKEFVAYLKKSFNYSRAESQQRALKKVAQL
VLNVSILWIGANLVMDGKMSLGQLITYNSLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVESEFSEKKNVQDLSLT
SGDIKFNDVSYRYGYGKDVLSEINLHIKRGSKVAFVGISGSGKTTLAKMIVSFFEPSKGEISLNNVNLNQIDKHALRQHI
NYLPQQPYVFNGTILENLLLGAREGTTQEDIMKAVELAEIKSDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDS
PVLILDEATSNLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEHVVVLDKGKIIEQGTHRDLVSQNGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=506384 I2433_RS07825 WP_111677831.1 1611018..1613171(-) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGAAATTTAGAAGAAAACACTACCGTGCTCAGGTTGATACTCGCGATTGTGGCGTAGCTTCTCTGGCCATGATTTACGG
TTATTATGGATCGTATTATTCGCTAGCAACGTTACGTGAAGCTGCAAAGACAACGCAGGAAGGGACTACAGCTTTTGGTT
TAGTCAAAGTTTCTGAGGCGCTTGGGTTTGAAACGAGAGCTATTAGGGCTGACATGAGTTTATTTGATGTGGAAGGATTA
TCTTATCCTTTTATTGCCCATGTTCTAAAAAAAGGTAAGTTCCTTCATTATTATGTGGTAACAGGACAAGATAAAAAATA
TATTCATATTGCAGATCCAGATCCAACTGTAAAGTTGACTTGTCTTTCTCGTCAGCGATTTGCTTCAGAGTGGACAGGTG
TGACAATTTTTATCGCTCCTACTCCTGAATACAAACCTCACAAGGAAAAGAAAAATAGTCTGCTAGATTTTGTGCCTCTC
CTAGCAAAGCAAAAAGGATTGATTACTAATATCGTTGTGGCAACGCTTTTGGTAACGATTATCAATATTATTGGTTCGTA
TTATCTTCAATCAATCATTGATACCTATGTTCCTAGTGTGATGAAGAATACACTAGGTATTATTTCCGTAGGTTTGGTTA
TTGTCTATGCCCTTCAACAAGTGATCTCATATGCGCAAGAGTATTTATTGCTGATATTAGGGCAACGTTTATCTATTGAT
GTAATTCTTTCTTATATCAAACATATTTTCAACCTTCCTATGTCTTTTTTCGCGACGAGAAGGACCGGGGAAATTGTTTC
TCGTTTTAATGATGCTAATTCAATCATTGATGCTTTAGCAAGTACAATTTTATCTATTTTCCTTGATGTTTCTGTCATTG
TAATTATATCTCTTGTTCTTTTTTCGCAAAATGTAAATCTATTTGTTATCAGTTTGCTTGCTCTGCCTATCTATGCAGTG
ATTATCTTTGCCTTCATGAAGCCATTTGAACGGATGAATCAAGAGACAATGGAAGCAAATTCAATCATGTCATCTTCTAT
TATTGAAGATATAAACGGTATTGAGACTATTAAATCATTAACTAGCGAAAAGATAAGATACCAAAAAATAGATAAAGAAT
TTGTAGCTTATCTTAAGAAATCTTTCAACTATAGTAGGGCAGAAAGCCAACAACGAGCATTGAAAAAAGTAGCTCAGCTT
GTCCTAAACGTGAGCATACTCTGGATAGGAGCCAATCTGGTTATGGACGGAAAAATGAGTTTAGGTCAACTGATTACCTA
TAACTCTCTCCTAATCTACTTTACAAATCCTCTGGAGAATATTATCAATCTTCAAACGAAACTTCAAACCGCTCAAGTCG
CTAATAATCGATTGAATGAGGTATATCTAGTTGAATCCGAGTTCTCTGAAAAGAAGAATGTTCAAGACTTATCTTTGACC
TCTGGTGACATAAAATTCAATGATGTTAGCTATCGATATGGATATGGAAAAGATGTTTTATCAGAAATAAATTTGCATAT
TAAACGAGGAAGCAAGGTTGCTTTTGTTGGGATTTCAGGTTCTGGAAAAACGACTTTAGCTAAGATGATTGTCAGTTTCT
TTGAACCAAGCAAAGGCGAAATATCATTAAATAATGTGAATCTAAATCAAATTGACAAACATGCTCTTCGCCAGCACATT
AACTATCTTCCTCAACAACCTTACGTATTTAATGGGACAATCCTTGAGAATTTACTTCTTGGAGCACGTGAAGGGACGAC
TCAAGAAGACATTATGAAGGCAGTAGAATTGGCTGAAATCAAGTCTGATATTGAACGTATGCCTTTGAATTATCAAACAG
AGTTAACCTCAGATGGTGCAGGGATTTCTGGAGGTCAACGTCAACGTATTGCCTTAGCAAGGGCATTATTGACAGATTCT
CCTGTTTTGATATTAGACGAAGCTACAAGTAACTTGGATATTTTGACTGAGAAGCGAATTGTTGATAACCTGATGGCTTT
AGATAAAACCTTGATATTTATTGCTCACCGTTTAACTATTGCAGAGCGTACAGAGCATGTCGTCGTTTTGGATAAAGGAA
AGATCATAGAGCAAGGAACACACAGAGACCTTGTTTCTCAGAATGGCTTTTATGCTCACTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (6-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	82.148	100	0.821
comA	Streptococcus mitis SK321	81.729	100	0.817
comA	Streptococcus pneumoniae Rx1	81.729	100	0.817
comA	Streptococcus pneumoniae D39	81.729	100	0.817
comA	Streptococcus pneumoniae R6	81.729	100	0.817
comA	Streptococcus pneumoniae TIGR4	81.45	100	0.815
comA	Streptococcus gordonii str. Challis substr. CH1	78.522	100	0.785
comA/nlmT	Streptococcus mutans UA159	62.762	100	0.628