Detailed information NTG0506382

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: I2433_RS07665
• Genome accession: NZ_CP065056
• Coordinates: 1574999..1576036 (-)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ14
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1569999..1581036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2433_RS07640 (JDBNIEOD_01536)	-	1570296..1570529 (-)	234	WP_012678314.1	YqgQ family protein	-
I2433_RS07645 (JDBNIEOD_01537)	-	1570895..1571425 (-)	531	WP_012515230.1	Dps family protein	-
I2433_RS07650 (JDBNIEOD_01538)	-	1571776..1572273 (+)	498	WP_249068055.1	peptidase	-
I2433_RS07655 (JDBNIEOD_01539)	rlmN	1572700..1573782 (-)	1083	WP_206152074.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
I2433_RS07660 (JDBNIEOD_01540)	-	1573786..1574400 (-)	615	WP_196819920.1	YutD family protein	-
I2433_RS07665 (JDBNIEOD_01541)	sepM	1574999..1576036 (-)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
I2433_RS07670 (JDBNIEOD_01542)	coaD	1576014..1576514 (-)	501	WP_043983724.1	pantetheine-phosphate adenylyltransferase	-
I2433_RS07675 (JDBNIEOD_01543)	rsmD	1576504..1577043 (-)	540	WP_012515220.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
I2433_RS07680 (JDBNIEOD_01544)	asnA	1577212..1578204 (-)	993	WP_012515219.1	aspartate--ammonia ligase	-
I2433_RS07685 (JDBNIEOD_01545)	arcC	1578424..1579374 (-)	951	WP_012678323.1	carbamate kinase	-
I2433_RS07690 (JDBNIEOD_01546)	-	1579392..1580723 (-)	1332	WP_206152076.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=506382 I2433_RS07665 WP_014622492.1 1574999..1576036(-) (sepM) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=506382 I2433_RS07665 WP_014622492.1 1574999..1576036(-) (sepM) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTGGTGAGCCTCAGTCGGGCTACCTTGGCTAAATTGCTTTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGATTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTACCAGGCCCTTACTCTAGCAGGTAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701