Detailed information NTG0506381

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I2433_RS07550
• Genome accession: NZ_CP065056
• Coordinates: 1549753..1552008 (+)
• Length: 751 a.a.
• NCBI ID: WP_206152065.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ14
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1544753..1557008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2433_RS07530 (JDBNIEOD_01514)	-	1546059..1546796 (-)	738	WP_042670303.1	amino acid ABC transporter ATP-binding protein	-
I2433_RS07535 (JDBNIEOD_01515)	-	1546798..1547481 (-)	684	WP_012679178.1	amino acid ABC transporter permease	-
I2433_RS07540 (JDBNIEOD_01516)	-	1547893..1548795 (+)	903	WP_206152063.1	LPXTG cell wall anchor domain-containing protein	-
I2433_RS07545 (JDBNIEOD_01517)	-	1549240..1549470 (-)	231	WP_012515249.1	DUF1797 family protein	-
I2433_RS07550 (JDBNIEOD_01518)	clpE	1549753..1552008 (+)	2256	WP_206152065.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I2433_RS07555 (JDBNIEOD_01519)	-	1552156..1552602 (+)	447	WP_043025456.1	NUDIX hydrolase	-
I2433_RS07560 (JDBNIEOD_01520)	-	1552664..1552966 (+)	303	WP_012515246.1	DUF1827 family protein	-
I2433_RS07565 (JDBNIEOD_01521)	ileS	1553438..1556236 (-)	2799	WP_206152067.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83899.23 Da
• Isoelectric Point: 5.4936

>NTDB_id=506381 I2433_RS07550 WP_206152065.1 1549753..1552008(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHDGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDAMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLRIVHLMLDDVNQRLAHNSIHLDVTEKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPTEKNLRAVLTSNGHITIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=506381 I2433_RS07550 WP_206152065.1 1549753..1552008(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGACGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGACCCAG
TCATCGGACGAGATGATGAGATTATCCGCGTCATCGAAATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAGGAAATCCGCAAGCGCCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTGGGAGCCGGG
GCAGTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
CACCACTCTCAATGAATACCGCATTATCGAAAAGGACGCAGCCCTCGAACGACGCATGCAGCCGGTTAAGGTGGACGAGC
CTTCGGTTGAAGAAACAATCACTATCCTAAAAGGAATCCAACCCAAATATGAGGACTATCACCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCTGCTAACCTCTCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTGCT
AGATGAAGCCGGCTCAAAGATGAACCTAACCCTTAACTTTGTTGACCCCAAAGACATTGATAAGCGTTTGATTGAGGCTG
AAAACCTCAAGACACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTATTTCCGCGATCAAATCGCCAAATATAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATATTCCAATCATCACTGACAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGATGCTGTTGATAAAATTGCAAAAGCTATCCGTCGTAATCGTGTTGGACTGGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGCCCAACTGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAATATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCACGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCCGGCTACGTCGGCTATGAGGAGGCAGGTCAGTTAACAGAGCAGGTACGTCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATTGAAAAGGCTCACCCTGATGCGATGCACATGTTTTTACAGGTCCTAGATGACGGACGATTAACCGACGGACA
AGGACGGACCGTTAGCTTTAAGGATACTATTATCATCATGACATCAAATGCCGGCACCGGCAAAACAGAAGCTTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAATTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGTCCCGAATTTATGAAC
CGCTTTGACGGGATTATTGAGTTTCAGCCGCTAAGCAAGGACAATCTGCTACGTATCGTTCACTTAATGCTTGATGACGT
TAATCAGCGCCTTGCTCACAATAGCATTCACCTTGATGTGACCGAAAAGGTCAAGGAAAAGCTCGTCGAGCTAGGCTATG
ATCCCAAGATGGGAGCACGACCACTGCGCCGCACCATTCAGGATTACATTGAGGACGCTATTACAGACTTTTACCTTGAG
CACCCAACTGAAAAGAACCTGCGAGCTGTTTTGACCTCTAATGGACACATTACAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (295-392)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-726)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.367	98.802	0.834
clpE	Streptococcus pneumoniae Rx1	81.83	100	0.822
clpE	Streptococcus pneumoniae D39	81.83	100	0.822
clpE	Streptococcus pneumoniae R6	81.83	100	0.822
clpE	Streptococcus pneumoniae TIGR4	81.698	100	0.82
clpC	Lactococcus lactis subsp. cremoris KW2	76.776	97.47	0.748
clpC	Bacillus subtilis subsp. subtilis str. 168	49.926	90.146	0.45
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.877	88.815	0.407
clpC	Streptococcus pneumoniae Rx1	48.052	82.024	0.394
clpC	Streptococcus pneumoniae D39	48.052	82.024	0.394
clpC	Streptococcus pneumoniae TIGR4	47.89	82.024	0.393
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus mutans UA159	47.182	82.69	0.39
clpC	Streptococcus thermophilus LMG 18311	46.19	83.888	0.387