Detailed information NTG0506370

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: JGX27_RS11010
• Genome accession: NZ_CP077423
• Coordinates: 2201763..2204333 (-)
• Length: 856 a.a.
• NCBI ID: WP_009855174.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus TX20005
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2196763..2209333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JGX27_RS10980 (JGX27_10980)	-	2196853..2197026 (-)	174	WP_009855168.1	hypothetical protein	-
JGX27_RS10985 (JGX27_10985)	-	2197076..2197540 (-)	465	WP_009855169.1	hypothetical protein	-
JGX27_RS10990 (JGX27_10990)	-	2197610..2198017 (-)	408	WP_009855170.1	hypothetical protein	-
JGX27_RS10995 (JGX27_10995)	-	2198180..2199034 (+)	855	WP_009855171.1	helix-turn-helix transcriptional regulator	-
JGX27_RS11000 (JGX27_11000)	ruvA	2199108..2199701 (-)	594	WP_009855172.1	Holliday junction branch migration protein RuvA	Machinery gene
JGX27_RS11005 (JGX27_11005)	hexB	2199703..2201646 (-)	1944	WP_009855173.1	DNA mismatch repair endonuclease MutL	Machinery gene
JGX27_RS11010 (JGX27_11010)	hexA	2201763..2204333 (-)	2571	WP_009855174.1	DNA mismatch repair protein MutS	Machinery gene
JGX27_RS11015 (JGX27_11015)	-	2204320..2204676 (-)	357	WP_009855175.1	YlbF family regulator	-
JGX27_RS11020 (JGX27_11020)	argR	2204673..2205110 (-)	438	WP_003066930.1	arginine repressor	-
JGX27_RS11025 (JGX27_11025)	argS	2205301..2206992 (+)	1692	WP_009855176.1	arginine--tRNA ligase	-
JGX27_RS11030 (JGX27_11030)	-	2207105..2207398 (+)	294	WP_009855177.1	bacteriocin immunity protein	-
JGX27_RS11035 (JGX27_11035)	-	2207439..2208944 (-)	1506	WP_009855178.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95896.23 Da
• Isoelectric Point: 4.8516

>NTDB_id=506370 JGX27_RS11010 WP_009855174.1 2201763..2204333(-) (hexA) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
MTKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSLSDFTS
LRSEILNLKAREVVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQAQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPTIKAILESFESPHLDKLVNNIDTLPELESLIRSAIAP
DAPAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRGQVERYITRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASSQSLILFDELGRGTATYDGMALAQSIIEYIHNHIGAKTMFATHYHEL
TALSTSLTHLINVHVATLEKNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPEVEVG
PITVKSEVAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=506370 JGX27_RS11010 WP_009855174.1 2201763..2204333(-) (hexA) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
ATGACAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGACGTAAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAAGCTGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCAATTCCAATGGCAGGTGTGCCTTATCATTCTGCGCAACAATACATTGATGTATTAGTG
GAAATGGGTTACAAGGTGGCAATTGCTGAGCAAATGGAAGACCCAAAACAAGCCGTCGGTGTGGTTAAACGTGAAGTCGT
TCAAGTGATTACGCCAGGAACAGCTGTCGATTCCTCTAAACCAGATAATGCTAACAATTTCTTGGTGGCTATCGATTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGACGTGTCAACAGGTGAATTTTTCTCAACAAGTCTTTCTGATTTTACAAGC
CTTAGAAGTGAAATTCTGAACCTTAAAGCGCGTGAAGTTGTTGTTGGTTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCTTATCGTTTGAACAAGAACGTTATGAAGATGTGCATTTAATCGACCCAGATTTAACGG
CTTTAGAAATTTCAGCAGCTGAGAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGCCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTATACGACAAAATCTAGTCTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTATTGCGCAATT
GGATTGACCGTCCTTTGGTGAACCAAGCACAGATTGAAGAGCGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTCAAAGGTGTTTATGATATTGAACGTTTAGCGAGTCGTGTGTCATTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACTTTGGCACAAGTGCCAACGATTAAGGCGATTTTAGAATCGTTTGAGA
GCCCTCACCTTGACAAGCTTGTCAACAACATTGACACTTTGCCAGAGCTAGAATCGCTGATTCGCTCAGCTATTGCCCCA
GATGCCCCTGCTGTTATCACAGAAGGTAGCATTATCCGTACAGGCTTTGATGAGACTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGCTGGATTGCAGAAATTGAAGCTAAGGAACGTGCTGCAAGTGGGATTACCAATCTAAAAATTGATT
ATAATAAAAAAGACGGATACTATTTCCATGTGACAAATTCCAATCTCTCTCTAGTGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCAAAAATTGAAGGTGAGATGTTGGAGGCGCGTGAGCAATC
AGCAAGCTTAGAATATGATATTTTCATGCGCGTTCGCGGACAAGTTGAGCGTTACATTACACGTTTGCAAGACTTGGCTA
AGGCGATTTCAACCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAAAATAATCATTATGTTCGTCCGACGTTCAAC
GATAGCCATGAAATTAAGATTGAAAAAGGTCGTCATGCGGTCGTTGAAAAAGTCATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAACTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACAGTTATTATGGCTCAAATGGGGTCTTACGTAGCTGCTGAAAGTGTCAATTTACCAGTATTTGATGCG
ATTTTCACGCGTATTGGTGCGGCAGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAACCA
AGCTATCAAACGTGCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATAATCATATCGGTGCAAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGCTTTGTCAACAAGCTTGACGCACCTTATCAATGTTCACGTTGCGACTCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGAATTCATGTAGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGCATTTTGACGAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGAGGTAGAAGTTGGG
CCAATTACTGTAAAATCTGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAACCAAGA
AGTGATTGAAGCACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.43	100	0.724
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382