Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   I6L86_RS07975 Genome accession   NZ_CP077259
Coordinates   1659191..1659655 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus mitis strain FDAARGOS 1456     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1654191..1664655
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L86_RS07945 (I6L86_07945) dhaL 1654995..1655570 (+) 576 WP_001100267.1 dihydroxyacetone kinase subunit DhaL -
  I6L86_RS07950 (I6L86_07950) dhaM 1655570..1655944 (+) 375 WP_000534739.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  I6L86_RS07955 (I6L86_07955) - 1656540..1657541 (+) 1002 WP_000344676.1 hypothetical protein -
  I6L86_RS07960 (I6L86_07960) - 1657538..1657735 (+) 198 WP_000658758.1 hypothetical protein -
  I6L86_RS07965 (I6L86_07965) - 1657774..1658466 (+) 693 WP_000120611.1 YjjG family noncanonical pyrimidine nucleotidase -
  I6L86_RS07970 (I6L86_07970) - 1658528..1659181 (+) 654 WP_000401338.1 uracil-DNA glycosylase -
  I6L86_RS07975 (I6L86_07975) mutX 1659191..1659655 (+) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  I6L86_RS07980 (I6L86_07980) - 1659668..1660936 (+) 1269 WP_000924473.1 dihydroorotase -
  I6L86_RS07985 (I6L86_07985) - 1660978..1662339 (+) 1362 WP_000283632.1 MATE family efflux transporter -
  I6L86_RS07990 (I6L86_07990) - 1662493..1663461 (+) 969 WP_000025262.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  I6L86_RS07995 (I6L86_07995) - 1663477..1664469 (+) 993 WP_000448715.1 alpha-ketoacid dehydrogenase subunit beta -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=506063 I6L86_RS07975 WP_001135768.1 1659191..1659655(+) (mutX) [Streptococcus mitis strain FDAARGOS 1456]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=506063 I6L86_RS07975 WP_001135768.1 1659191..1659655(+) (mutX) [Streptococcus mitis strain FDAARGOS 1456]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAACGGGAAAGAACTGCTTATGCTCCACCGTAATAAGAAGCCAAATGA
TGTTCATGAAGGAAAATGGATTGGTGTGGGTGGTAAGCTAGAGCGAGGAGAGACACCTCAGGAATGCGCGGCGCGTGAAA
TCCTTGAGGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTCGAGGGGGATTTGATTGACTGCAATGAGGGGACGCTGGAATGGGTTCC
TTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCATACCTTTGTTGAGTGGCTTTTAGAGGACAAACCCTTCT
TTTCAGCTAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTTTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987