Detailed information NTG0505860

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: I6L85_RS00560
• Genome accession: NZ_CP077248
• Coordinates: 89166..91709 (+)
• Length: 847 a.a.
• NCBI ID: WP_111724233.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS 1455
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 84166..96709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L85_RS00545 (I6L85_00545)	-	85569..86504 (+)	936	WP_111724234.1	YitT family protein	-
I6L85_RS00550 (I6L85_00550)	argS	86733..88421 (-)	1689	WP_012131026.1	arginine--tRNA ligase	-
I6L85_RS00555 (I6L85_00555)	argR	88550..88987 (+)	438	WP_008809983.1	arginine repressor	-
I6L85_RS00560 (I6L85_00560)	hexA	89166..91709 (+)	2544	WP_111724233.1	DNA mismatch repair protein MutS	Machinery gene
I6L85_RS00565 (I6L85_00565)	-	91758..92228 (-)	471	WP_111724232.1	DUF3021 family protein	-
I6L85_RS00570 (I6L85_00570)	-	92225..92665 (-)	441	WP_061599763.1	LytTR family DNA-binding domain-containing protein	-
I6L85_RS00575 (I6L85_00575)	hexB	92850..94793 (+)	1944	WP_111724231.1	DNA mismatch repair endonuclease MutL	Machinery gene
I6L85_RS00580 (I6L85_00580)	-	94829..95350 (-)	522	Protein_89	RDD family protein	-
I6L85_RS00585 (I6L85_00585)	-	95334..95837 (-)	504	WP_111724322.1	helix-turn-helix domain-containing protein	-
I6L85_RS00590 (I6L85_00590)	ruvA	96005..96598 (+)	594	WP_111724230.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 847 a.a.
• Molecular weight: 95159.52 Da
• Isoelectric Point: 4.9052

>NTDB_id=505860 I6L85_RS00560 WP_111724233.1 89166..91709(+) (hexA) [Streptococcus gordonii strain FDAARGOS 1455]
MATEKISPGMQQYLDIKKDYQDAFLLFRMGDFYELFYEDAVNAAQILEIALTSRNKNSENPIPMAGVPYHSAQQYIDVLI
ESGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPAGENNFLVALDRQEQAYGLAYMDLATGEFQVTSLSDFDQ
VCGEIRNLRAREVVVGYCLSEDEQQVLSKQMNLLLSEVKEAMDDVQLLGDELSSLEKQTAGKLLAYVFQTQMRELSHLKK
AHHYEIKDFLQMDYATKTSLDLSENARTGKKHGSLFWLMDETKTAMGGRLLRSWIQHPLIDKGRIIKRQDVVQVFLDYFF
ERSDLADSLKGVYDIERLVSRVSFGKTNPKDLLQLASTLSHVPQIRSILETIESPALESLVARLDAIPELENLISSAIDP
DAPQVITEGNIIRTGFDETLDQYRLVMREGTSWIADIEAKEREASGITNLKIDYNKKDGYYFHVTNSQLGNVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRVREEVGKYIQRLQALAQTLATVDVLQSFAVVAESQHLVRPSFT
SSRSLQIKKGRHAVVEKVMGAQSYIPNSIELDQETDIQLITGPNMSGKSTYMRQLAMIVIMAQMGSYVPAEVASLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANRAIRQASERSLILFDELGRGTATYDGMALAQAIIEYIHDRTKAKTLFATHYHEL
TDLSKSLTRLENVHVATLEKDGQVTFLHKIEAGPADKSYGIHVAKIAGLPKDLLTRADAILTDLENQVKREASLPASRTD
SQKVSEQMSLFVEETENPVLTELRDLDIYNMTPLEVMAAVAELKKKL

Nucleotide

• Length: 2544 bp

>NTDB_id=505860 I6L85_RS00560 WP_111724233.1 89166..91709(+) (hexA) [Streptococcus gordonii strain FDAARGOS 1455]
ATGGCAACAGAAAAAATATCGCCAGGTATGCAGCAGTACTTGGATATTAAAAAAGACTATCAGGACGCCTTCCTGCTGTT
TCGTATGGGTGATTTCTATGAGTTGTTTTACGAGGATGCTGTTAATGCGGCACAGATTCTCGAGATTGCCCTGACTAGCC
GTAATAAAAATTCGGAGAATCCCATTCCAATGGCGGGTGTACCTTATCATTCTGCCCAGCAGTATATTGATGTTTTGATT
GAGTCTGGTTATAAGGTTGCCATTGCGGAGCAGATGGAAGATCCTAAACAGGCCGTAGGTGTAGTCAAACGCGAGGTGGT
ACAGGTTATTACACCGGGTACGGTAGTGGATTCTAGTAAGCCGGCTGGAGAAAATAACTTTTTGGTTGCTTTGGATAGGC
AGGAGCAAGCTTATGGCTTGGCCTATATGGATCTGGCTACGGGAGAATTTCAGGTAACCAGCCTATCAGATTTTGACCAA
GTTTGTGGAGAAATTCGAAATCTCCGGGCTCGGGAAGTGGTCGTAGGTTATTGCTTGTCAGAAGATGAGCAACAGGTTTT
GTCAAAACAAATGAATTTACTCCTGTCAGAAGTCAAGGAGGCAATGGATGACGTTCAGCTCTTAGGAGATGAGTTGTCAT
CTTTAGAAAAGCAGACGGCAGGGAAGCTTTTGGCCTATGTTTTTCAGACGCAGATGCGGGAGCTCAGCCATCTCAAAAAG
GCCCATCATTATGAGATAAAAGATTTTCTTCAGATGGACTATGCGACAAAGACCAGTCTGGACTTGAGTGAAAATGCCCG
GACGGGCAAGAAGCATGGTAGTCTTTTTTGGCTTATGGATGAAACAAAAACAGCTATGGGAGGACGCTTGCTTCGTTCTT
GGATCCAGCATCCCTTGATTGATAAGGGACGAATTATCAAGCGTCAAGATGTTGTTCAGGTCTTTCTAGATTATTTCTTT
GAGCGGAGTGATTTGGCAGATAGTCTAAAGGGCGTCTATGATATTGAACGCCTGGTAAGTCGTGTGTCATTTGGCAAGAC
CAATCCCAAGGACCTCCTGCAATTGGCTTCTACTTTGAGCCATGTTCCTCAGATCCGGTCAATTTTAGAAACGATTGAAA
GCCCAGCTCTGGAGAGTTTGGTGGCAAGGCTAGATGCGATTCCTGAGCTGGAAAATCTAATCAGCTCTGCTATTGACCCA
GATGCTCCACAAGTAATTACTGAGGGCAATATCATTCGAACTGGTTTTGACGAGACTTTGGACCAGTACCGTTTGGTCAT
GAGAGAGGGGACTAGCTGGATTGCGGACATTGAAGCCAAGGAGCGAGAGGCAAGTGGTATTACTAATCTGAAAATTGATT
ATAACAAGAAAGATGGTTACTATTTCCATGTCACCAATTCTCAACTAGGCAATGTCCCTAGCCATTTTTTCCGGAAAGCA
ACCTTGAAAAATTCTGAGCGTTTTGGTACGGAAGAGCTGGCGCGCATTGAAGGCGAGATGCTGGAGGCGCGTGAGAAATC
TGCTAATCTGGAGTATGAGATCTTCATGCGCGTTCGTGAAGAAGTCGGGAAATATATTCAACGGCTACAAGCCTTAGCTC
AAACCCTAGCTACGGTCGATGTTTTACAGAGCTTTGCGGTTGTGGCTGAAAGTCAACACTTAGTCCGTCCAAGCTTTACA
AGCAGTCGTAGTTTGCAGATTAAAAAAGGCCGTCATGCGGTTGTCGAAAAAGTCATGGGAGCCCAAAGCTACATCCCAAA
TAGTATCGAACTGGATCAAGAAACAGATATTCAGCTGATTACCGGACCAAATATGAGCGGGAAGTCAACCTACATGCGAC
AGCTAGCAATGATTGTCATCATGGCTCAAATGGGATCATATGTACCAGCGGAAGTAGCCAGTCTTCCGATTTTCGATGCT
ATCTTTACACGAATAGGTGCAGCAGACGATTTGGTGTCTGGCCAATCAACCTTCATGGTAGAGATGATGGAGGCCAATCG
GGCCATTCGGCAAGCAAGTGAACGCTCTTTGATCCTTTTTGATGAACTGGGGCGGGGGACTGCGACTTATGATGGGATGG
CTCTGGCGCAAGCAATAATCGAGTATATTCATGATCGTACCAAGGCCAAGACTCTTTTTGCAACCCATTATCATGAGTTG
ACAGACCTGTCAAAGAGCTTGACACGGTTGGAAAACGTCCATGTGGCAACTCTAGAAAAAGATGGCCAAGTGACATTTTT
GCATAAGATTGAAGCAGGACCTGCTGATAAGTCCTATGGGATTCACGTGGCAAAAATTGCTGGTTTGCCAAAAGATTTAC
TGACAAGGGCAGATGCGATTTTGACAGATTTGGAAAATCAAGTGAAAAGAGAGGCTTCTCTTCCAGCGTCTAGGACGGAC
TCCCAAAAAGTGTCTGAGCAGATGTCGCTTTTTGTAGAAGAAACGGAAAATCCAGTCCTGACTGAACTCCGAGACTTGGA
CATCTACAATATGACTCCCCTAGAAGTTATGGCAGCAGTGGCTGAGTTGAAGAAGAAGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	77.804	100	0.778
mutS	Pseudomonas stutzeri strain ATCC 17587	36.86	100	0.374