Detailed information NTG0505819

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I6L84_RS07450
• Genome accession: NZ_CP077224
• Coordinates: 1523252..1525366 (-)
• Length: 704 a.a.
• NCBI ID: WP_012130882.1
• Uniprot ID: A8AZB2
• Organism: Streptococcus gordonii strain FDAARGOS 1454
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1518252..1530366

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L84_RS07430 (I6L84_07430)	eeP	1519513..1520769 (-)	1257	WP_197711255.1	RIP metalloprotease RseP	Regulator
I6L84_RS07435 (I6L84_07435)	-	1520926..1521729 (-)	804	WP_012130880.1	phosphatidate cytidylyltransferase	-
I6L84_RS07440 (I6L84_07440)	-	1521738..1522487 (-)	750	WP_008809837.1	isoprenyl transferase	-
I6L84_RS07445 (I6L84_07445)	yajC	1522747..1523079 (-)	333	WP_012130881.1	preprotein translocase subunit YajC	-
I6L84_RS07450 (I6L84_07450)	clpC	1523252..1525366 (-)	2115	WP_012130882.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6L84_RS07455 (I6L84_07455)	-	1525617..1527608 (-)	1992	WP_060553841.1	sucrose-specific PTS transporter subunit IIBC	-
I6L84_RS07460 (I6L84_07460)	-	1527807..1529261 (+)	1455	WP_060553840.1	sucrose-6-phosphate hydrolase	-
I6L84_RS07465 (I6L84_07465)	-	1529242..1530207 (+)	966	WP_060553839.1	LacI family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 704 a.a.
• Molecular weight: 77743.63 Da
• Isoelectric Point: 4.8276

>NTDB_id=505819 I6L84_RS07450 WP_012130882.1 1523252..1525366(-) (clpC) [Streptococcus gordonii strain FDAARGOS 1454]
MNNNYNNFNNMDDLFNQLMAGMRGYNSENRRYLINGREVTPEEFAQYRATGKLPGQGTGEQDLQTAGHGPKQDGILAKLG
RNLTQEARDGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISVDISGL
EAGTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEHEIAEQKDKQEAAVEKEDFEAALNAKTRIEELEKKIQNHTEDMKVTATVNDVAESVERMTGVPVSQMGA
SDIERLKGMNDRLKAKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKEAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEAGLEEDAEKPDLMDRLKAYFRPEFLNRFNAVIEFSHLKKEDLMEIVNLMLIEVNQTLSKKEIDLAVS
DAAKEFLRDAGYDQVMGVRPLRRVIEQQIRDKVTDFHLDHLDAKHLTADLEDGVLVIKEKEGAE

Nucleotide

• Length: 2115 bp

>NTDB_id=505819 I6L84_RS07450 WP_012130882.1 1523252..1525366(-) (clpC) [Streptococcus gordonii strain FDAARGOS 1454]
ATGAATAACAATTACAACAATTTTAATAATATGGATGACTTATTTAATCAATTAATGGCTGGAATGCGTGGTTACAATAG
TGAAAACCGTCGTTACCTCATTAACGGCCGTGAAGTGACGCCAGAAGAATTTGCACAATATCGTGCTACTGGTAAACTAC
CTGGTCAAGGAACGGGTGAACAGGATTTACAAACTGCTGGTCATGGACCTAAGCAAGATGGCATCCTGGCTAAGCTGGGT
CGCAATCTGACTCAGGAAGCGCGTGATGGAAAGTTAGATCCAGTCATTGGGCGTAATAAGGAAATCCAAGAAACTGCTGA
AATCCTTTCTCGCCGGACTAAGAACAATCCAGTTCTGGTCGGCGATGCTGGAGTTGGTAAGACAGCTGTCGTAGAAGGTT
TGGCTCAAGCTATTGTCAATGGTGATGTACCAGCAGCTATCAAGAATAAGGAAATCATTTCTGTTGATATTTCTGGTCTG
GAAGCTGGTACCCAGTATCGTGGTAGCTTTGAAGAAAATATCCAAAACTTGGTCAATGAAGTCAAGGAAGCTGGCAACAT
CATCCTATTCTTTGATGAAATCCATCAAATTCTAGGAGCAGGATCTACCGGTGGAGATAGTGGCTCTAAGGGACTAGCGG
ATATTCTCAAACCAGCGCTTTCTCGTGGTGAGTTGACAGTTATCGGAGCTACTACTCAGGATGAGTACCGTAATACTATT
CTCAAAAATGCAGCTCTAGCTCGTCGTTTCAATGAAGTTAAAGTCAATGCACCGTCTGCCGAAGATACCTATAAAATTCT
TCAAGGTATCCGAGACTTGTACGAAAAGCACCACAATGTCATCCTGCCAGATGAAGTACTGAAAGCTGCTGTGGACTACT
CTGTTCAGTATATTCCACAAAGGAGCTTGCCAGATAAGGCAATCGACCTTGTTGATGTAACGGCAGCCCACTTGGCGGCT
CAACATCCAGTGACTGATGTCCATGCGGTTGAACATGAGATCGCTGAGCAAAAAGACAAGCAGGAAGCCGCTGTTGAAAA
AGAAGATTTCGAAGCAGCTCTGAATGCCAAGACTCGTATCGAAGAACTAGAAAAGAAAATTCAAAACCACACTGAGGATA
TGAAGGTGACTGCAACAGTCAACGATGTGGCAGAATCTGTTGAACGTATGACGGGTGTACCAGTATCTCAAATGGGTGCT
AGTGATATTGAGCGCCTCAAGGGCATGAATGACCGTCTCAAAGCTAAAGTAATCGGCCAAGACAAGGCTGTAGAAGCTGT
GGCTAGAGCTATCCGCCGTAACCGTGCAGGTTTTGACGAAGGAAATCGCCCAATTGGTAGCTTCCTCTTTGTTGGTCCAA
CTGGTGTAGGTAAGACTGAGCTTGCTAAGCAATTAGCTCTAGATATGTTCGGTACTAAAGAGGCCATCATCCGTCTGGAT
ATGTCTGAATACTCTGACCGGACTGCTGTTTCCAAGCTGATTGGTACCACTGCGGGTTATGTTGGCTATGATGACAACAA
CAATACTTTGACCGAGCGTGTTCGTCGAAATCCATACTCTATCATTCTCTTGGATGAGATTGAAAAGGCTGATCCGCAAG
TGATTACCCTTCTCCTTCAAGTTCTGGATGACGGCCGTTTGACAGATGGTCAAGGGAATACAGTTAACTTCAAGAACACA
GTCATCATTGCGACTTCCAATGCTGGATTTGGCTATGAAGCTGGCTTAGAAGAAGATGCAGAAAAACCTGATCTGATGGA
CCGACTCAAAGCTTACTTCCGTCCAGAATTCCTCAATCGTTTCAATGCGGTTATTGAGTTCTCTCATCTCAAGAAAGAGG
ACTTGATGGAAATTGTGAATCTCATGTTGATTGAAGTAAATCAAACCTTGAGCAAGAAAGAAATTGATCTAGCTGTATCT
GATGCAGCTAAGGAATTCCTGCGTGACGCTGGTTATGACCAAGTCATGGGTGTTCGTCCACTCCGCCGTGTCATTGAGCA
ACAAATCCGTGACAAGGTGACCGATTTCCACTTGGATCATTTAGATGCTAAGCACTTGACAGCTGATTTGGAAGATGGTG
TCTTGGTTATTAAGGAAAAGGAGGGGGCTGAGTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (610-680)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-603)

• AAA lid domain (AAA_lid_9) (259-354)

3D structure

• AlphaFold DB: A8AZB2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	50.462	92.33	0.466
clpE	Streptococcus mutans UA159	49.533	91.193	0.452
clpE	Streptococcus pneumoniae Rx1	48.452	91.761	0.445
clpE	Streptococcus pneumoniae D39	48.452	91.761	0.445
clpE	Streptococcus pneumoniae R6	48.452	91.761	0.445
clpE	Streptococcus pneumoniae TIGR4	48.212	91.335	0.44
clpC	Bacillus subtilis subsp. subtilis str. 168	45.692	92.33	0.422
clpC	Streptococcus pneumoniae D39	43.087	88.352	0.381
clpC	Streptococcus pneumoniae TIGR4	43.087	88.352	0.381
clpC	Streptococcus pneumoniae Rx1	43.087	88.352	0.381
clpC	Streptococcus thermophilus LMG 18311	42.811	87.926	0.376
clpC	Streptococcus mutans UA159	42.673	88.21	0.376
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.019	87.5	0.376
clpC	Streptococcus thermophilus LMD-9	42.301	87.642	0.371