Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC   Type   Regulator
Locus tag   SII_RS09860 Genome accession   NC_022237
Coordinates   1957393..1957539 (-) Length   48 a.a.
NCBI ID   WP_003075491.1    Uniprot ID   O33651
Organism   Streptococcus intermedius C270     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 1952393..1962539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS09505 (SII_1864) - 1952402..1954978 (+) 2577 WP_020999301.1 YfhO family protein -
  SII_RS09520 (SII_1867) comE 1955302..1956051 (-) 750 WP_003075488.1 competence system response regulator transcription factor ComE Regulator
  SII_RS09525 (SII_1868) comD/comD1 1956051..1957376 (-) 1326 WP_003075490.1 GHKL domain-containing protein Regulator
  SII_RS09860 (SII_1869) comC 1957393..1957539 (-) 147 WP_003075491.1 bacteriocin Regulator
  SII_RS09540 (SII_1871) rlmH 1957816..1958295 (-) 480 WP_003075603.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SII_RS09545 (SII_1872) htrA 1958499..1959689 (+) 1191 WP_020999302.1 S1C family serine protease Regulator
  SII_RS09550 (SII_1873) spo0J 1959744..1960511 (+) 768 WP_020999303.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence


Protein


Download         Length: 48 a.a.        Molecular weight: 5605.69 Da        Isoelectric Point: 10.5532

>NTDB_id=50575 SII_RS09860 WP_003075491.1 1957393..1957539(-) (comC) [Streptococcus intermedius C270]
MKKLFAKKEVVKKEVVKFKELNDEQLDKVIGGDSRIRMGFDFSKLFGK

Nucleotide


Download         Length: 147 bp        

>NTDB_id=50575 SII_RS09860 WP_003075491.1 1957393..1957539(-) (comC) [Streptococcus intermedius C270]
ATGAAAAAGTTGTTTGCTAAAAAAGAGGTAGTAAAAAAGGAAGTTGTGAAATTTAAAGAGTTAAATGATGAACAGTTAGA
TAAAGTTATTGGTGGGGATAGTCGAATCAGAATGGGATTTGATTTTTCTAAACTTTTTGGTAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB O33651

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus sinensis strain Forsyth1A

54.054

77.083

0.417


Multiple sequence alignment