Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPPC18_RS03975 Genome accession   NC_017742
Coordinates   839278..841062 (+) Length   594 a.a.
NCBI ID   WP_000774413.1    Uniprot ID   -
Organism   Helicobacter pylori PeCan18     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 834278..846062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPPC18_RS03945 (HPPC18_04030) motB 834997..835770 (+) 774 WP_001085364.1 flagellar motor protein MotB -
  HPPC18_RS03950 (HPPC18_04035) - 835767..836213 (+) 447 WP_001081242.1 hypothetical protein -
  HPPC18_RS03955 (HPPC18_04040) - 836327..837988 (+) 1662 WP_000901310.1 ABC transporter permease/substrate-binding protein -
  HPPC18_RS03960 (HPPC18_04045) - 837992..838633 (+) 642 WP_000665992.1 ABC transporter ATP-binding protein -
  HPPC18_RS03965 - 838645..838824 (-) 180 WP_000468794.1 hypothetical protein -
  HPPC18_RS03970 (HPPC18_04050) - 838816..839277 (+) 462 WP_000437221.1 hypothetical protein -
  HPPC18_RS03975 (HPPC18_04055) uvrC 839278..841062 (+) 1785 WP_000774413.1 excinuclease ABC subunit UvrC Machinery gene
  HPPC18_RS03980 (HPPC18_04060) - 841072..842337 (+) 1266 WP_000746756.1 homoserine dehydrogenase -
  HPPC18_RS03985 (HPPC18_04065) - 842337..842681 (+) 345 WP_001211690.1 YraN family protein -
  HPPC18_RS03990 (HPPC18_04070) trxA 842770..843090 (+) 321 WP_000020199.1 thioredoxin -
  HPPC18_RS03995 (HPPC18_04075) trxB 843096..844031 (+) 936 WP_000564381.1 thioredoxin-disulfide reductase -
  HPPC18_RS04000 (HPPC18_04080) - 844401..845222 (+) 822 WP_001263382.1 glycosyltransferase family 25 protein -
  HPPC18_RS04005 (HPPC18_04085) - 845433..845681 (-) 249 WP_000790551.1 RNA recognition motif domain-containing protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68689.92 Da        Isoelectric Point: 9.7910

>NTDB_id=50562 HPPC18_RS03975 WP_000774413.1 839278..841062(+) (uvrC) [Helicobacter pylori PeCan18]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEGKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
DCSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECMPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=50562 HPPC18_RS03975 WP_000774413.1 839278..841062(+) (uvrC) [Helicobacter pylori PeCan18]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTTTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ACCCTCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATCTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGAGCTAAGGACATTTTGGATAGTTTGTATGAATTGCTCCCATTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGGTAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCTAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGACATTTTTGCTTTTTATGGTGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAACGGGTTTGACA
CTGATGAAGCGATGAAGCAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GATTGCTCTAATGAAGTGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCATGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATCTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGTTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.133

99.832

0.97

Multiple sequence alignment