Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SII_RS08340 Genome accession   NC_022237
Coordinates   1731430..1733550 (-) Length   706 a.a.
NCBI ID   WP_020999189.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1726430..1738550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS08310 (SII_1638) - 1726514..1727221 (-) 708 WP_003074030.1 L-ribulose-5-phosphate 4-epimerase -
  SII_RS08315 (SII_1639) - 1727224..1728087 (-) 864 WP_020999187.1 L-ribulose-5-phosphate 3-epimerase -
  SII_RS08320 (SII_1640) - 1728093..1728758 (-) 666 WP_020999188.1 3-keto-L-gulonate-6-phosphate decarboxylase UlaD -
  SII_RS08325 (SII_1641) - 1728804..1729289 (-) 486 WP_003074024.1 PTS sugar transporter subunit IIA -
  SII_RS08330 (SII_1642) - 1729491..1729772 (-) 282 WP_003074022.1 PTS sugar transporter subunit IIB -
  SII_RS08335 (SII_1643) - 1729803..1731263 (-) 1461 WP_009569486.1 PTS ascorbate transporter subunit IIC -
  SII_RS08340 (SII_1644) clpE 1731430..1733550 (-) 2121 WP_020999189.1 AAA family ATPase Regulator
  SII_RS08345 (SII_1645) - 1733928..1734233 (-) 306 WP_009569488.1 hypothetical protein -
  SII_RS08350 - 1734233..1734643 (-) 411 WP_041823286.1 hypothetical protein -
  SII_RS08355 (SII_1646) - 1734625..1735881 (-) 1257 WP_020999190.1 lipase family alpha/beta hydrolase -
  SII_RS08360 (SII_1647) - 1735878..1736270 (-) 393 WP_020999191.1 DUF1310 family protein -
  SII_RS08365 (SII_1648) - 1736313..1736495 (-) 183 WP_009569494.1 hypothetical protein -
  SII_RS08370 (SII_1649) - 1736498..1736884 (-) 387 WP_020999192.1 DUF1310 family protein -
  SII_RS08375 (SII_1650) - 1737110..1737496 (-) 387 WP_020999193.1 DUF1310 family protein -
  SII_RS08380 - 1737551..1737733 (-) 183 WP_041823287.1 hypothetical protein -
  SII_RS08385 (SII_1651) - 1737730..1738122 (-) 393 WP_020999194.1 DUF1310 family protein -

Sequence

Protein


Download         Length: 706 a.a.        Molecular weight: 78522.75 Da        Isoelectric Point: 4.8757

>NTDB_id=50552 SII_RS08340 WP_020999189.1 1731430..1733550(-) (clpE) [Streptococcus intermedius C270]
MNNNFDNMDDLFNQLMGRMGGFNSENRRYLINGREVTPEEFAQYRATGKLPKQVAEGQASQMQGQAGELKQDGILMKLGR
NLTEEARQDMLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDISGLE
AGTQYRGSFEENIQNLVSEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTIL
KNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILSDDVLKAAVDFSIQYIPQRSLPDKAIDLVDVTAAHLAAQ
HPVTDVHTVEREIAEQKKKQEAAVEKEDFETALNAKMRIEELEKKIENHTEDMKVTATVNDVAESVERMTGIPVSQMGTS
DIERLKEMNARLKTKVIGQNEAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKEAIIRLDM
SEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTV
IIATSNAGFGYESFTGDEEKDRKIIDRLKPYFRPEFLNRFNAVIEFSHLGKEDLAEIVDLMLDEVNQTLAKKDIMLTVTD
AAKHYLAEEGYDEVMGVRPLRRVIEQQIRDKVTDYHLDHLDAKHLLADLKDDELVIKEAKEHQTKK

Nucleotide


Download         Length: 2121 bp        

>NTDB_id=50552 SII_RS08340 WP_020999189.1 1731430..1733550(-) (clpE) [Streptococcus intermedius C270]
ATGAACAACAACTTTGATAATATGGATGATCTTTTCAATCAATTGATGGGAAGGATGGGCGGTTTTAACAGTGAAAATCG
GCGTTATCTTATCAATGGACGTGAAGTGACACCAGAAGAATTTGCACAATATCGTGCAACAGGTAAATTACCGAAGCAAG
TAGCGGAAGGTCAGGCATCACAAATGCAAGGACAAGCAGGTGAGCTTAAACAAGATGGTATTTTAATGAAGTTAGGGCGT
AATTTGACAGAAGAAGCACGTCAAGATATGTTAGATCCTGTTATTGGACGCAATAAGGAAATTCAAGAAACGGCTGAAAT
TCTTTCTCGGCGAACGAAAAACAATCCAGTATTAGTCGGAGACGCTGGAGTTGGTAAGACTGCAGTTGTCGAAGGTTTAG
CGCAAGCGATTGTTAATGGAGATGTTCCTGCAGCCATTAAGAATAAAGAGATTGTTTCTATTGATATTTCTGGTTTAGAA
GCAGGGACACAGTATCGTGGTAGTTTTGAAGAAAATATTCAAAATTTAGTATCTGAAGTGAAAGAGGCTGGCAATATCAT
TCTCTTCTTTGATGAAATTCATCAAATTCTGGGCGCTGGAAGCACAGGCGGTGATAGTGGATCAAAAGGTCTAGCAGATA
TTTTGAAACCGGCTTTATCTCGTGGTGAACTGACAGTTATCGGTGCGACGACTCAGGATGAATATCGAAATACCATTTTG
AAGAATGCAGCTCTAGCTCGTCGCTTCAATGAAGTAAAAGTCAATGCCCCATCTGCAGAAGATACTTACAAGATTTTGCA
AGGAATTCGTGATTTATACGAAAAACACCACAATGTCATCTTGTCAGATGACGTGTTAAAAGCTGCCGTGGATTTCTCTA
TTCAATACATTCCGCAACGCAGCTTGCCGGATAAAGCGATTGACCTGGTGGATGTGACAGCGGCTCATTTAGCAGCTCAA
CATCCTGTTACAGATGTGCATACAGTAGAACGTGAAATTGCGGAGCAAAAGAAAAAGCAAGAAGCTGCGGTTGAAAAAGA
AGACTTTGAAACTGCTTTGAATGCCAAGATGCGTATTGAAGAGCTAGAAAAAAAGATTGAAAATCATACGGAAGACATGA
AAGTAACTGCAACTGTCAATGATGTAGCAGAATCTGTAGAACGTATGACGGGTATTCCTGTTTCCCAAATGGGGACTAGT
GATATTGAACGGTTGAAAGAGATGAATGCGCGATTGAAGACAAAAGTCATTGGACAAAACGAAGCAGTTGAAGCAGTGGC
GCGCGCTATTCGTCGGAATCGTGCAGGTTTTGATGAAGGAAATCGTCCGATTGGTAGCTTTCTCTTTGTTGGCCCAACTG
GTGTTGGAAAAACAGAGCTAGCGAAGCAATTGGCGCTGGATATGTTTGGTACTAAAGAAGCTATTATCCGTTTGGACATG
TCTGAATACTCTGACCGCACAGCTGTGTCGAAATTGATTGGTACAACAGCTGGTTATGTGGGGTATGATGACAATAGTAA
CACGTTGACAGAACGTGTTCGTCGGAATCCTTACTCTATCATCTTGCTGGACGAAATTGAAAAAGCCGATCCGCAAGTCA
TCACGCTGTTACTGCAAGTTTTAGATGATGGACGTCTGACAGATGGACAAGGAAATACTGTCAACTTTAAGAATACAGTT
ATTATTGCTACATCAAATGCTGGATTTGGGTATGAAAGCTTTACTGGTGATGAGGAAAAGGATAGGAAGATTATCGATCG
CTTAAAACCATACTTCCGTCCAGAATTCTTGAATCGCTTCAATGCAGTCATTGAATTCTCTCATCTTGGTAAAGAAGATT
TAGCTGAAATCGTCGACTTGATGTTGGATGAGGTCAACCAAACACTTGCTAAGAAAGACATTATGCTAACAGTAACAGAT
GCGGCCAAACATTATCTAGCAGAAGAGGGATATGATGAAGTTATGGGTGTTCGTCCGCTTCGTCGTGTGATTGAGCAACA
AATCCGTGATAAGGTAACAGACTATCATCTTGATCATTTAGATGCGAAACATCTTCTTGCAGATTTGAAAGATGATGAAT
TAGTTATCAAAGAAGCGAAAGAGCATCAAACTAAAAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(258-353)

ATPase family associated with various cellular activities (AAA) (AAA)

(117-249)

AAA domain (Cdc48 subfamily) (AAA_2)

(442-602)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(609-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.262

100

0.465
  clpC Lactococcus lactis subsp. cremoris KW2

51.347

89.377

0.459
  clpE Streptococcus pneumoniae R6

45.098

100

0.456
  clpE Streptococcus pneumoniae D39

45.098

100

0.456
  clpE Streptococcus pneumoniae Rx1

45.098

100

0.456
  clpE Streptococcus pneumoniae TIGR4

44.866

100

0.452
  clpC Bacillus subtilis subsp. subtilis str. 168

47.214

91.501

0.432
  clpC Streptococcus pneumoniae Rx1

42.613

91.076

0.388
  clpC Streptococcus pneumoniae D39

42.613

91.076

0.388
  clpC Streptococcus pneumoniae TIGR4

42.457

91.076

0.387
  clpC Streptococcus mutans UA159

43.922

87.394

0.384
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.506

87.252

0.38
  clpC Streptococcus thermophilus LMD-9

42.626

87.394

0.373
  clpC Streptococcus thermophilus LMG 18311

42.464

87.394

0.371

Multiple sequence alignment