Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPPC18_RS00100 Genome accession   NC_017742
Coordinates   14464..16827 (+) Length   787 a.a.
NCBI ID   WP_000890489.1    Uniprot ID   -
Organism   Helicobacter pylori PeCan18     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9464..21827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPPC18_RS00070 (HPPC18_00045) groES 9482..9838 (-) 357 WP_000671927.1 co-chaperone GroES -
  HPPC18_RS00075 (HPPC18_00050) dnaG 10125..11804 (+) 1680 WP_000601594.1 DNA primase -
  HPPC18_RS00080 (HPPC18_00055) - 11801..12853 (+) 1053 WP_000809435.1 MnmA/TRMU family protein -
  HPPC18_RS00085 (HPPC18_00060) - 12945..13772 (+) 828 WP_001154951.1 DUF5718 family protein -
  HPPC18_RS00090 (HPPC18_00065) comB2 13918..14199 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HPPC18_RS00095 (HPPC18_00070) comB3 14199..14462 (+) 264 WP_000584948.1 hypothetical protein Machinery gene
  HPPC18_RS00100 (HPPC18_00075) comB4 14464..16827 (+) 2364 WP_000890489.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPPC18_RS00105 (HPPC18_00080) - 17132..18472 (+) 1341 WP_001876830.1 COG3014 family protein -
  HPPC18_RS00110 (HPPC18_00085) cheV1 18578..19543 (+) 966 WP_000785508.1 chemotaxis protein CheV1 -
  HPPC18_RS00115 (HPPC18_00090) nspC 19540..20757 (+) 1218 WP_000760814.1 carboxynorspermidine decarboxylase -
  HPPC18_RS00120 (HPPC18_00095) lpxE 20794..21327 (-) 534 WP_228921234.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90288.67 Da        Isoelectric Point: 8.2538

>NTDB_id=50551 HPPC18_RS00100 WP_000890489.1 14464..16827(+) (comB4) [Helicobacter pylori PeCan18]
MLEKLLGTIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQNIQSDSKYLQAILNQFENKEVYENQYFLVLESTHSLHGVLEHKKKSFMHANRENFKDILS
YKAHFLQETFKSLEIQLKNYAPKLLNSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGVKAYESERITSIAVGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLILGLLLKENLVGVIETFGLKGGYFSFFPERIYLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISYLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYRILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=50551 HPPC18_RS00100 WP_000890489.1 14464..16827(+) (comB4) [Helicobacter pylori PeCan18]
ATGTTAGAAAAGCTTTTAGGCACTATCAAGCAAAAAGTTTCAAATTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCAAT
GAGTGAAGAAAACAATATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACTGAACGCCAAATGGCGTTGGAT
TCTTTGGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAACATTCAATCTGACTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAGAATCAGTATTTTTTGGTTTTAGAAAGCACTC
ACTCTTTGCATGGCGTTTTGGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGAGAAAATTTTAAGGATATTCTTTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTTAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAACTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCTTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCCATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCGTTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGCTTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACCAGCTTAATTTTAGGGCTTTTACTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGAGGGTATTTTTCCTTTTTCCCTGAACGCATTTATTTAAACC
ACCGCTTGCGTTTTTTGACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCCAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCATAATAACGCTAAAGAAATCGCTAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTATTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGATAGGATGCAAGGGCTG
TATTCTTTTACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTCGATCTCGCCCCCTCAAGAGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGCGCGATTAAGAGCCTTTATGAGACCCTATACCCCAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGCTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAACGTGATAAACCTAGATGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAGGATCTTAGAAGAGTCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAGTTAAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTATCCGCAAAAAAACGCTAGGGAATTGAAACACAATTTCAATGTGCCTTTGAGCGAGACTGAAATTTCA
TTTTTAGAAAACACGCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCCAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAGATCTTTAATTCGGATTCTAGTCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

96.569

100

0.966

Multiple sequence alignment