Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   IYN86_RS00490 Genome accession   NZ_CP064868
Coordinates   99519..101147 (-) Length   542 a.a.
NCBI ID   WP_001186596.1    Uniprot ID   -
Organism   Mammaliicoccus sciuri strain 82104     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 81350..102514 99519..101147 within 0


Gene organization within MGE regions


Location: 81350..102514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IYN86_RS00390 mecA 81350..83359 (-) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  IYN86_RS00395 mecR1 83456..85213 (+) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  IYN86_RS00400 mecI 85213..85584 (+) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  IYN86_RS00405 psm-mec 85669..85737 (-) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  IYN86_RS00410 - 86057..87205 (+) 1149 WP_000427807.1 ROK family transcriptional regulator -
  IYN86_RS00415 cstB 87319..88653 (-) 1335 Protein_81 persulfide dioxygenase-sulfurtransferase CstB -
  IYN86_RS00420 - 88687..89751 (-) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  IYN86_RS00425 cstR 89887..90147 (+) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  IYN86_RS00430 - 90147..90785 (+) 639 Protein_84 sulfite exporter TauE/SafE family protein -
  IYN86_RS00440 - 91059..91676 (-) 618 WP_000562107.1 CadD family cadmium resistance transporter -
  IYN86_RS00445 - 91757..94171 (-) 2415 WP_000378485.1 cadmium-translocating P-type ATPase CadA -
  IYN86_RS00450 - 94164..94529 (-) 366 WP_000159127.1 metalloregulator ArsR/SmtB family transcription factor -
  IYN86_RS00455 - 94767..95144 (-) 378 WP_001041908.1 DUF6262 family protein -
  IYN86_RS00460 - 95151..97043 (-) 1893 WP_248559301.1 site-specific integrase -
  IYN86_RS00465 - 97238..97561 (-) 324 WP_000088091.1 JAB domain-containing protein -
  IYN86_RS00470 - 97554..97760 (-) 207 WP_001077283.1 hypothetical protein -
  IYN86_RS00475 - 97762..98283 (-) 522 WP_000836008.1 DUF1643 domain-containing protein -
  IYN86_RS00480 - 98302..98613 (-) 312 WP_000833212.1 DUF960 family protein -
  IYN86_RS00485 - 98698..99048 (-) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  IYN86_RS00490 ccrB 99519..101147 (-) 1629 WP_001186596.1 recombinase family protein Machinery gene
  IYN86_RS00495 ccrA 101168..102514 (-) 1347 WP_000816499.1 recombinase family protein Machinery gene

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62274.15 Da        Isoelectric Point: 9.7334

>NTDB_id=505441 IYN86_RS00490 WP_001186596.1 99519..101147(-) (ccrB) [Mammaliicoccus sciuri strain 82104]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=505441 IYN86_RS00490 WP_001186596.1 99519..101147(-) (ccrB) [Mammaliicoccus sciuri strain 82104]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

86.531

100

0.865