Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   IYN86_RS00295 Genome accession   NZ_CP064868
Coordinates   61296..62648 (-) Length   450 a.a.
NCBI ID   WP_107522616.1    Uniprot ID   -
Organism   Mammaliicoccus sciuri strain 82104     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 52954..61279 61296..62648 flank 17


Gene organization within MGE regions


Location: 52954..62648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IYN86_RS00245 - 52963..53112 (+) 150 WP_248559291.1 abortive infection family protein -
  IYN86_RS00250 - 53304..53711 (+) 408 WP_248559292.1 hypothetical protein -
  IYN86_RS15590 - 53844..53969 (+) 126 WP_282579069.1 hypothetical protein -
  IYN86_RS00255 - 54661..55722 (+) 1062 WP_248559293.1 DNA methyltransferase -
  IYN86_RS00260 - 55680..56690 (+) 1011 WP_248559294.1 TaqI-like C-terminal specificity domain-containing protein -
  IYN86_RS00265 - 56687..56908 (+) 222 WP_248559295.1 hypothetical protein -
  IYN86_RS00270 - 57028..57717 (-) 690 WP_107378646.1 replication initiation protein -
  IYN86_RS00275 - 57918..58421 (-) 504 WP_107378647.1 DUF1643 domain-containing protein -
  IYN86_RS00280 - 58442..58753 (-) 312 WP_107378648.1 DUF960 family protein -
  IYN86_RS00285 - 58838..59187 (-) 350 Protein_55 SAUGI family uracil-DNA glycosylase inhibitor -
  IYN86_RS00290 ccrB 59648..61279 (-) 1632 WP_107378649.1 recombinase family protein Machinery gene
  IYN86_RS00295 ccrA 61296..62648 (-) 1353 WP_107522616.1 recombinase family protein Machinery gene

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 52581.27 Da        Isoelectric Point: 9.9580

>NTDB_id=505440 IYN86_RS00295 WP_107522616.1 61296..62648(-) (ccrA) [Mammaliicoccus sciuri strain 82104]
MKQAIGYLRQSTLKQQSLTAQKQTIETLAKKYNIQHITFYSDKQSGRTDNRTGYQQVIERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGLKEKARQGKLITTHAPFGYTYH
NGTFTINQDEAPTVKAIFHYYLQGYGYKKIAQYLETDNQNINRKPYQVRAIIMNPNYCGRVINQYGQYDNMFPPIISISS
YEQAQILRSEKHRKRTPSANQLKQKIKCPCCGATLTNMTIRRKQYNTLRYYVCPRNMNESRFVCDFKGINAKDIETSVLK
TCQHFFQDQQVYSKINDAIQQHIQKQNTLETKRTYTQAQLINKLAKGTIDAEIFKTEIQNLHQQNTLTSINSKRIQSAFH
NVIQKCFTLNILYPYIDVIHITENKTLTGIYFKNEPLNIVNQTKQSSIVS

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=505440 IYN86_RS00295 WP_107522616.1 61296..62648(-) (ccrA) [Mammaliicoccus sciuri strain 82104]
ATGAAACAAGCTATCGGTTACTTACGTCAAAGTACACTCAAACAACAATCACTCACTGCACAGAAACAAACTATCGAAAC
GCTCGCTAAAAAATACAATATCCAACACATCACCTTTTATAGTGATAAGCAATCAGGCAGAACGGATAATCGAACGGGTT
ACCAACAAGTTATCGAACGCATTCAACAAAGACAATGTGATGTATTATGTTGTTATCGCTTGAATCGACTACATCGTAAT
TTGAAAAATGCATTAAAACTTATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAGCTCAATATATTCATAAGCCTCGCAGAATTAGAGTCTGATAATATTGGTGAAC
AAGTCAAGAATGGCCTTAAAGAAAAAGCTAGACAAGGTAAACTCATCACGACACATGCACCATTTGGCTATACCTATCAC
AATGGTACATTCACAATTAATCAAGATGAAGCTCCAACGGTGAAGGCAATATTCCATTACTACCTACAAGGCTATGGTTA
TAAAAAAATTGCGCAATACCTAGAAACAGATAATCAAAACATCAATCGTAAACCCTACCAAGTACGCGCTATTATCATGA
ATCCTAATTACTGTGGTCGCGTTATCAATCAATATGGACAATATGACAACATGTTTCCACCTATTATTTCTATCAGTAGC
TATGAACAAGCGCAGATTTTACGTTCTGAAAAACATCGCAAACGAACACCTTCAGCTAATCAACTGAAACAAAAAATCAA
ATGTCCATGCTGTGGCGCCACACTTACAAATATGACAATTAGAAGAAAGCAATATAATACATTACGTTATTATGTCTGTC
CTCGAAATATGAATGAATCTCGTTTTGTCTGTGACTTTAAAGGGATTAACGCTAAAGATATAGAAACAAGTGTTTTAAAA
ACATGTCAACACTTCTTTCAAGACCAACAGGTCTATTCCAAAATAAATGATGCCATTCAACAACACATCCAAAAACAAAA
CACACTGGAAACTAAGCGCACGTACACCCAAGCACAACTCATCAATAAGTTAGCCAAAGGAACGATAGATGCAGAAATAT
TCAAAACAGAAATACAAAACTTACACCAACAAAATACACTGACATCTATCAATTCTAAGCGCATCCAAAGCGCATTTCAT
AATGTAATACAAAAATGTTTCACGTTAAACATCTTGTATCCTTATATTGATGTCATTCATATTACTGAAAACAAGACACT
TACAGGTATTTATTTCAAAAATGAACCACTGAATATCGTTAATCAAACTAAACAATCATCGATTGTATCATAA

Domains

Predicted by InterproScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-323)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

75.556

100

0.756
  ccrA Staphylococcus aureus N315

72

100

0.72