Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   IXY24_RS12920 Genome accession   NZ_CP064845
Coordinates   2632708..2633364 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain BZR 277     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2627708..2638364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IXY24_RS12900 (IXY24_12760) spxH 2627947..2628849 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  IXY24_RS12905 (IXY24_12765) - 2629135..2629302 (+) 168 WP_003155026.1 hypothetical protein -
  IXY24_RS12910 (IXY24_12770) pepF 2629340..2631169 (-) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  IXY24_RS12915 (IXY24_12775) - 2631397..2632557 (-) 1161 WP_044053100.1 competence protein CoiA family protein -
  IXY24_RS12920 (IXY24_12780) mecA 2632708..2633364 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  IXY24_RS12925 (IXY24_12785) - 2633347..2633457 (-) 111 Protein_2549 adaptor protein MecA -
  IXY24_RS12930 (IXY24_12790) - 2633640..2634296 (+) 657 WP_003155033.1 TerC family protein -
  IXY24_RS12935 (IXY24_12795) spx 2634354..2634749 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  IXY24_RS12940 (IXY24_12800) - 2634928..2635506 (-) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  IXY24_RS12945 (IXY24_12805) - 2635624..2636811 (-) 1188 WP_003155036.1 putative glycoside hydrolase -
  IXY24_RS12950 (IXY24_12810) oppF 2636918..2637835 (-) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=505215 IXY24_RS12920 WP_003155032.1 2632708..2633364(-) (mecA) [Bacillus velezensis strain BZR 277]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=505215 IXY24_RS12920 WP_003155032.1 2632708..2633364(-) (mecA) [Bacillus velezensis strain BZR 277]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895