Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   HPSH169_RS06660 Genome accession   NC_017740
Coordinates   1376222..1377535 (-) Length   437 a.a.
NCBI ID   WP_000653546.1    Uniprot ID   A0A0E0WD12
Organism   Helicobacter pylori Shi169     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1371222..1382535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSH169_RS06630 (HPSH169_06740) nadC 1371685..1372506 (-) 822 WP_000404040.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HPSH169_RS06635 (HPSH169_06745) nadA 1372506..1373516 (-) 1011 WP_001141822.1 quinolinate synthase NadA -
  HPSH169_RS06640 (HPSH169_06750) - 1373506..1374309 (-) 804 WP_000561117.1 phosphatidylserine decarboxylase -
  HPSH169_RS06645 (HPSH169_06755) - 1374306..1374809 (-) 504 WP_000953080.1 DUF6115 domain-containing protein -
  HPSH169_RS06650 (HPSH169_06760) - 1374822..1375316 (-) 495 WP_014662023.1 hypothetical protein -
  HPSH169_RS06655 (HPSH169_06765) mqnP 1375309..1376193 (-) 885 WP_000913959.1 menaquinone biosynthesis prenyltransferase MqnP -
  HPSH169_RS06660 (HPSH169_06770) comEC/comE3 1376222..1377535 (-) 1314 WP_000653546.1 ComEC/Rec2 family competence protein Machinery gene
  HPSH169_RS06665 (HPSH169_06775) - 1377532..1378992 (-) 1461 WP_000349790.1 replicative DNA helicase -
  HPSH169_RS06670 (HPSH169_06780) - 1379012..1380406 (-) 1395 WP_000954043.1 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase -
  HPSH169_RS06675 (HPSH169_06785) crdS 1380409..1381611 (-) 1203 WP_080024984.1 copper-sensing histidine kinase CrdS -
  HPSH169_RS06680 (HPSH169_06790) crdR 1381577..1382218 (-) 642 WP_001169800.1 copper response regulator transcription factor CrdR -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50119.06 Da        Isoelectric Point: 9.8368

>NTDB_id=50521 HPSH169_RS06660 WP_000653546.1 1376222..1377535(-) (comEC/comE3) [Helicobacter pylori Shi169]
MKDKTFQGAFELLATPKEYLLCGVVLSLLLALNLYLEYLNYQKLDFSKPTSLNAQILLQYPKTKDQKTYFVLKLQSKGMI
FYATIKEPLKNLQYRYAQFFGKIKPCSFLESLKSCFFQTYSFSLTREQDFKSHWRHFIDSAHSSALVGNLYRALFIGDSL
NKNLRDRANALGINHLLAISGFHLGILSASVYFLFSLFYAPLQKRYFPYRNAFYDIGVLVWVFLLGYLLLLDFLPSFFRA
FLMGLLGFLACFFGVRLLSFKLLILACCIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHTQAFFKTSSFLVRSFQVISLS
ALIFLNMLIIAHAFFPMFSPYQLFSIPLGLIFIVFFPLSLFLHAVGLGSLLDRILNMPLTIPTISVFSPLWLLGAHLFLT
ILSARFFKVYLSMNVLSAGFFLYCCYQYIIMPSLIVG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=50521 HPSH169_RS06660 WP_000653546.1 1376222..1377535(-) (comEC/comE3) [Helicobacter pylori Shi169]
TTGAAAGATAAAACTTTTCAGGGGGCGTTTGAACTTCTTGCAACCCCCAAAGAATACTTGTTGTGTGGGGTTGTTTTAAG
CCTTTTGTTAGCGCTCAATCTTTATTTAGAATATTTGAATTACCAAAAGCTTGATTTTTCAAAACCTACAAGCCTGAACG
CTCAAATCTTGTTGCAATACCCTAAAACTAAAGATCAAAAAACCTATTTTGTTTTAAAGCTCCAATCAAAGGGCATGATC
TTTTATGCCACCATTAAAGAGCCTTTAAAAAACCTCCAATACCGCTACGCGCAATTTTTTGGCAAAATCAAACCTTGCTC
ATTTCTGGAGTCTTTAAAATCATGCTTTTTTCAAACTTATTCTTTTTCTTTAACACGGGAACAAGATTTCAAATCGCATT
GGCGCCATTTCATTGATAGCGCTCATTCAAGCGCTTTAGTGGGGAATTTATACCGCGCGTTGTTTATAGGGGATAGCTTG
AATAAAAACTTAAGAGATAGGGCTAACGCGCTAGGGATCAACCACTTACTAGCCATTAGCGGGTTCCATTTAGGGATTTT
GAGCGCGAGCGTGTATTTCCTTTTCTCTCTTTTTTATGCCCCCTTACAAAAACGCTATTTCCCTTATAGGAACGCTTTTT
ATGATATAGGGGTTTTGGTGTGGGTTTTTTTGCTAGGGTATTTATTGCTATTGGATTTTTTACCCTCTTTTTTCAGGGCG
TTTTTAATGGGCTTGTTAGGGTTTTTGGCATGCTTTTTTGGGGTAAGGCTTTTGAGTTTTAAACTTTTGATTTTAGCGTG
CTGTATCGCTATAGCGTTACTCCCTAAATTGCTTTTTAGCGTGGGGTTTTTGCTTTCTGTTTGTGGGGTGTGGTATATCT
TTTTATTTTTAAAACACACTCAAGCCTTTTTTAAAACTTCTTCTTTTTTGGTGCGATCTTTTCAGGTCATAAGCTTAAGC
GCGCTAATTTTTTTAAACATGCTCATTATTGCGCATGCCTTTTTCCCTATGTTTTCGCCCTACCAGCTCTTTAGCATTCC
TTTAGGCTTGATTTTTATCGTGTTTTTCCCTTTGAGTTTGTTCTTGCATGCTGTGGGTTTGGGGTCTTTGTTGGATCGTA
TTTTAAACATGCCTTTAACAATCCCTACGATTTCGGTTTTTTCGCCTTTATGGCTTTTGGGGGCGCATTTATTTTTAACG
ATTCTAAGCGCGCGTTTTTTTAAAGTTTATTTAAGCATGAATGTTTTAAGCGCGGGCTTTTTCTTGTATTGTTGCTATCA
ATATATTATAATGCCTAGTTTAATTGTAGGTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(159-378)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E0WD12

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

94.508

100

0.945

Multiple sequence alignment