Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SII_RS05945 Genome accession   NC_022237
Coordinates   1225685..1227001 (+) Length   438 a.a.
NCBI ID   WP_020998896.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1220685..1232001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS05900 (SII_1164) - 1220790..1221110 (-) 321 WP_020998890.1 hypothetical protein -
  SII_RS05905 - 1221146..1221373 (-) 228 WP_041823245.1 hypothetical protein -
  SII_RS05910 (SII_1165) - 1221467..1221760 (-) 294 WP_020998891.1 bacteriocin immunity protein -
  SII_RS05915 (SII_1166) - 1221989..1222204 (-) 216 WP_041823339.1 bacteriocin class II family protein -
  SII_RS09765 (SII_1167) - 1222415..1222666 (-) 252 WP_020998893.1 hypothetical protein -
  SII_RS05920 (SII_1168) - 1222981..1223202 (-) 222 WP_003025422.1 Blp family class II bacteriocin -
  SII_RS05925 (SII_1169) - 1223210..1223530 (-) 321 WP_003037422.1 hypothetical protein -
  SII_RS05930 (SII_1170) - 1223618..1223842 (-) 225 WP_003025424.1 Blp family class II bacteriocin -
  SII_RS05935 (SII_1171) - 1224048..1224737 (+) 690 WP_020998895.1 CPBP family intramembrane glutamic endopeptidase -
  SII_RS05940 (SII_1172) comE/blpR 1224937..1225683 (+) 747 WP_037582857.1 response regulator transcription factor Regulator
  SII_RS05945 (SII_1173) comD/blpH 1225685..1227001 (+) 1317 WP_020998896.1 sensor histidine kinase Regulator
  SII_RS05950 (SII_1174) - 1227082..1227234 (-) 153 WP_003073362.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SII_RS05955 (SII_1175) - 1227331..1228692 (-) 1362 WP_020998897.1 bacteriocin secretion accessory protein -
  SII_RS05960 (SII_1176) comA/nlmT 1228703..1230853 (-) 2151 WP_020998898.1 peptide cleavage/export ABC transporter Regulator
  SII_RS05965 (SII_1177) - 1231334..1231708 (+) 375 WP_041823246.1 hypothetical protein -

Sequence

Protein


Download         Length: 438 a.a.        Molecular weight: 49945.60 Da        Isoelectric Point: 6.8627

>NTDB_id=50518 SII_RS05945 WP_020998896.1 1225685..1227001(+) (comD/blpH) [Streptococcus intermedius C270]
MYILLQLFVIISEMACVPILYSLISGKEFNILTYISIILGNFIIGILLMSTPENFINYLIHPIYFIVISWILGKEGSTTL
KIFYALFPITLINILHRLIGIFILPLFGVSVNILNASLLGNRLLSIFTSVIAFVFLKGNQYQFHSLADQSINYKDKRILV
ITNVSMVLYYIILQLLAYIEYTKFTTTLFVREALVIIYLVFFLIITNRLDLHLRERIQNDLMLQKDLQLKNLENYSHHIE
ELYTEVRSFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIGRLVHIKNDALKSLLAAKFAQAQEHN
VSVSLEVPEDICPQGMELVDFITIVSILCDNAIEAAAPTMTIAYVLSENKQVFSIENAIKEEHIDMSYIFDAGVSSKGSG
RGIGLSNVLAILDRYPNVSLASTSQNHCFQHILEIHLN

Nucleotide


Download         Length: 1317 bp        

>NTDB_id=50518 SII_RS05945 WP_020998896.1 1225685..1227001(+) (comD/blpH) [Streptococcus intermedius C270]
ATGTATATACTATTACAACTTTTTGTAATTATATCAGAGATGGCTTGTGTACCTATTTTATATTCATTGATCAGCGGAAA
GGAGTTCAATATATTAACCTATATTTCTATAATATTAGGCAATTTTATTATAGGTATTTTGTTAATGTCTACCCCTGAAA
ATTTTATAAATTATTTAATTCATCCAATTTATTTTATTGTGATTTCGTGGATACTTGGAAAAGAAGGAAGTACTACCTTA
AAAATATTTTATGCACTTTTTCCTATTACTTTAATTAATATTTTACATCGCTTAATAGGAATTTTTATTCTTCCTTTGTT
TGGAGTTAGTGTAAACATACTAAATGCTAGCTTACTGGGAAATAGACTTCTCTCTATTTTTACATCAGTGATAGCATTTG
TATTTCTAAAAGGAAATCAATATCAGTTTCATAGCTTAGCGGACCAATCTATAAATTATAAAGACAAAAGAATTCTTGTT
ATTACAAATGTGAGTATGGTATTGTACTATATCATTCTCCAACTATTGGCGTATATAGAATACACTAAATTTACAACAAC
TCTTTTTGTTAGAGAAGCATTGGTTATTATTTATCTAGTATTCTTTTTGATTATTACTAACCGACTGGACCTTCATTTAC
GGGAGAGAATCCAAAATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAACTTGGAAAACTACAGTCATCACATTGAG
GAATTGTACACAGAAGTTCGGAGCTTTCGGCATGATTACGCAAATATTTTAACAACCTTGAAATTAGGAATTGAGCAAAA
TGATATAGGCATTGTAAAGAATGTTTATCATTCTGTTTTGAAAGATTCCAATAAGCGTTTTCGCAATCCCAAGTATGATA
TTGGACGGTTAGTCCATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAAT
GTATCCGTTTCATTGGAAGTTCCAGAAGATATTTGTCCACAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCCAT
TTTGTGTGATAATGCGATTGAAGCTGCCGCTCCAACTATGACGATTGCTTATGTTTTGTCAGAAAACAAGCAGGTATTCT
CCATTGAAAATGCTATAAAAGAAGAGCATATAGACATGTCTTATATTTTTGATGCGGGAGTTAGTTCTAAAGGATCTGGG
CGAGGAATTGGATTATCAAATGTCTTAGCAATTCTGGATCGATATCCAAATGTTTCACTTGCTAGTACTAGCCAGAATCA
CTGCTTTCAGCACATCCTTGAGATTCATCTGAATTAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(336-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.164

94.521

0.361

Multiple sequence alignment