Detailed information NTG0505106

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LLDRC3_RS10195
• Genome accession: NZ_CP064835
• Coordinates: 2005479..2007725 (-)
• Length: 748 a.a.
• NCBI ID: WP_063283627.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain DRC3
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2000479..2012725

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLDRC3_RS10175 (LLDRC3_1965)	-	2002006..2002467 (-)	462	WP_306171264.1	RNA pyrophosphohydrolase	-
LLDRC3_RS10180 (LLDRC3_1966)	def	2002615..2003250 (+)	636	WP_003130816.1	peptide deformylase	-
LLDRC3_RS10185 (LLDRC3_1967)	gap	2003393..2004406 (-)	1014	WP_003130818.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
LLDRC3_RS10190 (LLDRC3_1968)	-	2004579..2005049 (+)	471	WP_003130820.1	Rrf2 family transcriptional regulator	-
LLDRC3_RS10195 (LLDRC3_1969)	clpC	2005479..2007725 (-)	2247	WP_063283627.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LLDRC3_RS10200 (LLDRC3_1970)	-	2007776..2008114 (-)	339	WP_003130824.1	hypothetical protein	-
LLDRC3_RS10205 (LLDRC3_1971)	-	2008397..2009764 (-)	1368	WP_003130826.1	MFS transporter	-
LLDRC3_RS10210 (LLDRC3_1972)	-	2009929..2010672 (-)	744	WP_010905438.1	MurR/RpiR family transcriptional regulator	-
LLDRC3_RS10215 (LLDRC3_1973)	rpoD	2010787..2012130 (-)	1344	WP_003130829.1	RNA polymerase sigma factor RpoD	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83162.90 Da
• Isoelectric Point: 4.7623

>NTDB_id=505106 LLDRC3_RS10195 WP_063283627.1 2005479..2007725(-) (clpC) [Lactococcus lactis subsp. lactis strain DRC3]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAETKKNEATQAEDFEKAAHFRDQITKLRELQNHEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKEMV
ADLIDDKIVISNQAQETAETTDEEVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=505106 LLDRC3_RS10195 WP_063283627.1 2005479..2007725(-) (clpC) [Lactococcus lactis subsp. lactis strain DRC3]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTTAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACAGGTGGACGTGGTCCGCGCGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCGCAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTTGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGCCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAACGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCATGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGTCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGAGCCCCTCCAGGATATGTGGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCCTACAGTTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTGCAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGATTTGGTGCTGCTCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAGCTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATAATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTCCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATTTAGGTTACAATCCAGCAATGGGTGCTAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAACACCCTGAATACAAAGAAATGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAACAGCAGAAACGACTGATGAAGAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

• AAA lid domain (AAA_lid_9) (287-386)

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	97.861	100	0.979
clpE	Streptococcus mutans UA159	75.894	100	0.766
clpE	Streptococcus pneumoniae Rx1	75.408	98.396	0.742
clpE	Streptococcus pneumoniae D39	75.408	98.396	0.742
clpE	Streptococcus pneumoniae R6	75.408	98.396	0.742
clpE	Streptococcus pneumoniae TIGR4	75.408	98.396	0.742
clpC	Bacillus subtilis subsp. subtilis str. 168	51.672	87.968	0.455
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.635	81.952	0.39
clpC	Streptococcus pneumoniae Rx1	46.635	83.422	0.389
clpC	Streptococcus pneumoniae D39	46.635	83.422	0.389
clpC	Streptococcus pneumoniae TIGR4	46.635	83.422	0.389
clpC	Streptococcus thermophilus LMD-9	46.104	82.353	0.38
clpC	Streptococcus thermophilus LMG 18311	45.942	82.353	0.378
clpC	Streptococcus mutans UA159	45.631	82.62	0.377