Detailed information NTG0050508

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: HPSH169_RS00190
• Genome accession: NC_017740
• Coordinates: 32538..33593 (+)
• Length: 351 a.a.
• NCBI ID: WP_000786690.1
• Uniprot ID: A0A0E0WAC9
• Organism: Helicobacter pylori Shi169
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 27538..38593

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPSH169_RS00160 (HPSH169_00145)	-	27952..28365 (+)	414	WP_001023010.1	universal stress protein	-
HPSH169_RS00165 (HPSH169_00150)	-	28373..28648 (+)	276	WP_000784913.1	ATP-dependent Clp protease adaptor ClpS	-
HPSH169_RS00170 (HPSH169_00155)	-	28648..30870 (+)	2223	WP_001051543.1	AAA family ATPase	-
HPSH169_RS00175 (HPSH169_00160)	panD	30860..31210 (+)	351	WP_000142289.1	aspartate 1-decarboxylase	-
HPSH169_RS00180 (HPSH169_00165)	-	31221..31523 (+)	303	WP_000347918.1	YbaB/EbfC family nucleoid-associated protein	-
HPSH169_RS00185 (HPSH169_00170)	-	31523..32530 (+)	1008	WP_000468454.1	PDZ domain-containing protein	-
HPSH169_RS00190 (HPSH169_00175)	comB6	32538..33593 (+)	1056	WP_000786690.1	P-type conjugative transfer protein TrbL	Machinery gene
HPSH169_RS00195 (HPSH169_00180)	comB7	33609..33722 (+)	114	WP_001217864.1	hypothetical protein	Machinery gene
HPSH169_RS00200 (HPSH169_00185)	comB8	33719..34462 (+)	744	WP_000660502.1	type IV secretion system protein	Machinery gene
HPSH169_RS00205 (HPSH169_00190)	comB9	34462..35418 (+)	957	WP_014662053.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HPSH169_RS00210 (HPSH169_00195)	comB10	35411..36547 (+)	1137	WP_001045877.1	DNA type IV secretion system protein ComB10	Machinery gene
HPSH169_RS00215 (HPSH169_00200)	-	36617..38029 (+)	1413	WP_000694835.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 39749.68 Da
• Isoelectric Point: 9.0413

>NTDB_id=50508 HPSH169_RS00190 WP_000786690.1 32538..33593(+) (comB6) [Helicobacter pylori Shi169]
MKNDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSVVALAFMLFAYRSLKEQNFFSTSALTEALLFMGFFALFNY
ALKNPMRFYEFFQNAIFIAPNMIAQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQGLFLSVL
FAIIILVYLEVHVWCSLGVLFLAFGFFKTWRSVVVACLKKCFALGFYKPFLLLVGFLNVSVTKALIDAHVQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSFKETYKLATNLSANLSQNALNSLQYITTPPASSSVSSSISGSVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTINTKNEI

Nucleotide

• Length: 1056 bp

>NTDB_id=50508 HPSH169_RS00190 WP_000786690.1 32538..33593(+) (comB6) [Helicobacter pylori Shi169]
ATGAAAAATGACGCTTATGAGATTATCCTTTCTTGGTTTATCACGCCTCTCACGGCGATTTTAGGGCGTTTCGCTGAATT
TTTTCTCTACACCTTGCATGCGCAATTGGTGTTTAATAGCGTGGTCGCTTTGGCGTTCATGCTCTTTGCTTATAGGAGTT
TGAAAGAACAGAATTTCTTCAGCACCAGCGCGCTAACAGAAGCGTTATTGTTTATGGGGTTTTTTGCGCTTTTTAACTAC
GCTTTAAAAAATCCCATGCGTTTTTATGAATTTTTCCAAAACGCTATTTTTATTGCGCCTAACATGATCGCGCAAAGCCT
CTCTCAAAGCTTGAGCAACTTTTCTAACCACGCGCTTTCTTTAGATTTTATCTTTAATCATGGTTTTTATGCCCTTAGTT
TTATCAGCGATTTGAGCCATAATGAAATGTCTGTGTGGCTTTTTTTAAGCATTTTGCAAGGGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTAGAAGTGCATGTGTGGTGCTCTTTAGGGGTGCTGTTTTTAGCGTTTGGGTTTTT
TAAAACATGGAGGAGCGTTGTGGTTGCATGCCTAAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTGTTGTTGG
TGGGGTTTTTGAACGTGTCGGTTACTAAGGCTTTAATAGACGCTCATGTGCAAGAAAAACAAGACTTAAGCCTTTTATTG
GTGGTAGCGTTATTTTTGTGTTGCGTTTTTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CTTTAAAGAAACTTACAAACTCGCTACCAATTTGAGCGCCAACCTCAGCCAAAACGCCCTTAATTCCTTACAATATATCA
CGACCCCACCCGCTTCTTCTAGCGTTTCTTCTTCTATAAGCGGAAGCGTCTCTAAAGAAAAAGAAACGCATTCCCCCACA
TTCAAGGTAGAAACCACTCAATTGGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAAATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: A0A0E0WAC9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	97.151	100	0.972