Detailed information NTG0504651

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: IXH55_RS11675
• Genome accession: NZ_CP064772
• Coordinates: 2391166..2392209 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TCH32767
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2386166..2397209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IXH55_RS11645 (IXH55_11585)	-	2386651..2386761 (+)	111	WP_001790257.1	hypothetical protein	-
IXH55_RS11650 (IXH55_11590)	-	2386790..2387203 (+)	414	WP_001557448.1	hypothetical protein	-
IXH55_RS11655 (IXH55_11595)	-	2387634..2388620 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
IXH55_RS11660 (IXH55_11600)	map	2389092..2389850 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
IXH55_RS11665 (IXH55_11605)	-	2390067..2390453 (+)	387	WP_001110179.1	hypothetical protein	-
IXH55_RS11670 (IXH55_11610)	liaF	2390468..2391169 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
IXH55_RS11675 (IXH55_11615)	vraS	2391166..2392209 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
IXH55_RS11680 (IXH55_11620)	vraR	2392199..2392828 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
IXH55_RS11685 (IXH55_11625)	-	2392941..2394158 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
IXH55_RS11690 (IXH55_11630)	-	2394436..2394711 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
IXH55_RS11695 (IXH55_11635)	-	2394718..2395182 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
IXH55_RS11700 (IXH55_11640)	-	2395329..2395529 (+)	201	WP_000180460.1	DUF1128 family protein	-
IXH55_RS11705 (IXH55_11645)	-	2395532..2396788 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=504651 IXH55_RS11675 WP_001017131.1 2391166..2392209(+) (vraS) [Staphylococcus aureus strain TCH32767]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=504651 IXH55_RS11675 WP_001017131.1 2391166..2392209(+) (vraS) [Staphylococcus aureus strain TCH32767]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1