Detailed information NTG0504181

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: KQ221_RS21940
• Genome accession: NZ_CP076704
• Coordinates: 4549222..4550247 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli O8:H28 strain BMH-17-0027
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4544222..4555247

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KQ221_RS21930 (KQ221_21930)	rpmE	4546453..4546665 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
KQ221_RS21935 (KQ221_21935)	priA	4546868..4549066 (+)	2199	WP_001298972.1	primosomal protein N'	Machinery gene
KQ221_RS21940 (KQ221_21940)	cytR	4549222..4550247 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
KQ221_RS21945 (KQ221_21945)	ftsN	4550339..4551298 (+)	960	WP_000068834.1	cell division protein FtsN	-
KQ221_RS21950 (KQ221_21950)	hslV	4551391..4551921 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
KQ221_RS21955 (KQ221_21955)	hslU	4551931..4553262 (+)	1332	WP_001293343.1	HslU--HslV peptidase ATPase subunit	-
KQ221_RS21960 (KQ221_21960)	menA	4553329..4554255 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
KQ221_RS21965 (KQ221_21965)	rraA	4554348..4554833 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
KQ221_RS21970 (KQ221_21970)	zapB	4554918..4555163 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=504181 KQ221_RS21940 WP_000644904.1 4549222..4550247(+) (cytR) [Escherichia coli O8:H28 strain BMH-17-0027]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=504181 KQ221_RS21940 WP_000644904.1 4549222..4550247(+) (cytR) [Escherichia coli O8:H28 strain BMH-17-0027]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAACCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTCGCACCGGAACTGGAG
CTACCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATCTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628