Detailed information NTG0503902

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI11_RS04600
• Genome accession: NZ_CP064640
• Coordinates: 990018..991064 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG337
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 985018..996064

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI11_RS04575 (HWI11_04560)	isaB	986159..986695 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI11_RS04580 (HWI11_04565)	-	986846..987832 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI11_RS04585 (HWI11_04570)	map	988006..988761 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI11_RS04590 (HWI11_04575)	-	988919..989305 (+)	387	WP_001830382.1	hypothetical protein	-
HWI11_RS04595 (HWI11_04580)	liaF	989320..990021 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI11_RS04600 (HWI11_04585)	vraS	990018..991064 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI11_RS04605 (HWI11_04590)	vraR	991054..991683 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI11_RS04610 (HWI11_04595)	-	991740..992918 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI11_RS04615 (HWI11_04600)	-	993325..993609 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI11_RS04620 (HWI11_04605)	-	993617..994081 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI11_RS04625 (HWI11_04610)	-	994222..994437 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI11_RS04630 (HWI11_04615)	-	994439..995680 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=503902 HWI11_RS04600 WP_002486322.1 990018..991064(+) (vraS) [Staphylococcus epidermidis strain UMCG337]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=503902 HWI11_RS04600 WP_002486322.1 990018..991064(+) (vraS) [Staphylococcus epidermidis strain UMCG337]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917