Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SCRE_RS02630 Genome accession   NC_022236
Coordinates   514384..515070 (+) Length   228 a.a.
NCBI ID   WP_003069999.1    Uniprot ID   F9P4U8
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 509384..520070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS02610 (SCRE_0519) - 509522..510154 (+) 633 WP_020997666.1 DUF421 domain-containing protein -
  SCRE_RS02615 (SCRE_0520) - 510518..510778 (-) 261 WP_006267469.1 SemiSWEET family transporter -
  SCRE_RS02620 (SCRE_0521) metG 511025..513022 (+) 1998 WP_006267251.1 methionine--tRNA ligase -
  SCRE_RS02625 (SCRE_0522) - 513112..514421 (-) 1310 Protein_502 DUF2974 domain-containing protein -
  SCRE_RS02630 (SCRE_0523) braR 514384..515070 (+) 687 WP_003069999.1 response regulator transcription factor Regulator
  SCRE_RS02635 (SCRE_0524) - 515054..516034 (+) 981 WP_020997667.1 sensor histidine kinase -
  SCRE_RS02640 (SCRE_0525) - 516158..516916 (+) 759 WP_006267137.1 TraX family protein -
  SCRE_RS10795 - 517023..517151 (+) 129 WP_006267181.1 hypothetical protein -
  SCRE_RS02645 (SCRE_0526) - 517170..517937 (+) 768 WP_006267387.1 ABC transporter ATP-binding protein -
  SCRE_RS02650 (SCRE_0527) - 517930..519918 (+) 1989 WP_006267657.1 ABC transporter permease -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26304.60 Da        Isoelectric Point: 4.9992

>NTDB_id=50386 SCRE_RS02630 WP_003069999.1 514384..515070(+) (braR) [Streptococcus constellatus subsp. pharyngis C232]
MHKILLVEDDAVIRQQVKKMLEQWGFEVIAVEDFMQVLTIFVKEEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGGDDFVTKPFDNNVLLAKVQGLLRRSYEFGTDQSLLEYHGVILNLKSMDMMYDGEVIALTKNEFQIL
RVLFEHSGSIVSRDDLMKELWNSDFFIDDNTLSVNIARLRKKLEDAGLKSFIETKKGIGYGLTNEFSK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=50386 SCRE_RS02630 WP_003069999.1 514384..515070(+) (braR) [Streptococcus constellatus subsp. pharyngis C232]
ATGCACAAGATATTATTAGTGGAAGACGATGCCGTCATTCGTCAACAAGTCAAAAAAATGCTGGAACAATGGGGATTTGA
GGTGATTGCTGTAGAGGATTTTATGCAGGTGCTGACGATTTTTGTTAAGGAAGAACCGCATCTAGTCCTGATGGATATTG
GTCTACCGTTGTTTAATGGTTATCATTGGTGCCAAGAAATTCGCAAGATTTCTAAAGTGCCTATTATGTTTTTATCTTCA
CGTGATCAGGCGATGGATATTGTCATGGCGATTAACATGGGCGGAGATGATTTTGTCACCAAGCCATTTGACAATAATGT
CTTGCTGGCTAAGGTTCAAGGACTCTTGCGTCGTTCGTATGAATTTGGGACAGATCAAAGTTTGTTGGAATACCATGGGG
TTATTCTCAATCTCAAGTCCATGGATATGATGTATGATGGAGAAGTGATTGCGTTAACGAAAAATGAATTTCAAATTCTG
CGTGTGCTATTTGAGCATTCTGGCAGTATTGTTTCGCGTGATGATCTCATGAAAGAACTGTGGAACAGTGATTTCTTTAT
TGATGACAATACCTTATCAGTCAATATCGCCCGTCTGCGCAAGAAATTAGAAGATGCTGGACTGAAAAGTTTTATTGAAA
CCAAGAAAGGAATTGGGTACGGATTGACGAATGAATTCTCAAAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P4U8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

50

95.614

0.478

Multiple sequence alignment