Detailed information NTG0503753

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI15_RS04530
• Genome accession: NZ_CP064626
• Coordinates: 973516..974562 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG342
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 968516..979562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI15_RS04505 (HWI15_04495)	isaB	969657..970193 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI15_RS04510 (HWI15_04500)	-	970344..971330 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI15_RS04515 (HWI15_04505)	map	971504..972259 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI15_RS04520 (HWI15_04510)	-	972417..972803 (+)	387	WP_001830382.1	hypothetical protein	-
HWI15_RS04525 (HWI15_04515)	liaF	972818..973519 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI15_RS04530 (HWI15_04520)	vraS	973516..974562 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI15_RS04535 (HWI15_04525)	vraR	974552..975181 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI15_RS04540 (HWI15_04530)	-	975238..976416 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI15_RS04545 (HWI15_04535)	-	976823..977107 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI15_RS04550 (HWI15_04540)	-	977115..977579 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI15_RS04555 (HWI15_04545)	-	977720..977935 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI15_RS04560 (HWI15_04550)	-	977937..979178 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=503753 HWI15_RS04530 WP_002486322.1 973516..974562(+) (vraS) [Staphylococcus epidermidis strain UMCG342]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=503753 HWI15_RS04530 WP_002486322.1 973516..974562(+) (vraS) [Staphylococcus epidermidis strain UMCG342]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917