Detailed information    

insolico Bioinformatically predicted

Overview

Name   braS   Type   Regulator
Locus tag   HWI18_RS12270 Genome accession   NZ_CP064619
Coordinates   2448841..2449737 (-) Length   298 a.a.
NCBI ID   WP_002437988.1    Uniprot ID   A0A4Q9W434
Organism   Staphylococcus epidermidis strain UMCG345     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2443841..2454737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI18_RS12255 (HWI18_12145) - 2445273..2445863 (-) 591 WP_001830621.1 DUF4064 domain-containing protein -
  HWI18_RS12260 (HWI18_12150) - 2445967..2447979 (-) 2013 WP_002456335.1 ABC transporter permease -
  HWI18_RS12265 (HWI18_12155) - 2447981..2448730 (-) 750 WP_001830627.1 ABC transporter ATP-binding protein -
  HWI18_RS12270 (HWI18_12160) braS 2448841..2449737 (-) 897 WP_002437988.1 HAMP domain-containing sensor histidine kinase Regulator
  HWI18_RS12275 (HWI18_12165) braR 2449743..2450408 (-) 666 WP_001830679.1 response regulator transcription factor Regulator
  HWI18_RS12280 (HWI18_12170) - 2450439..2450618 (-) 180 WP_001830653.1 hypothetical protein -
  HWI18_RS12285 (HWI18_12175) - 2450916..2452385 (+) 1470 WP_002484631.1 alkaline phosphatase -
  HWI18_RS12290 (HWI18_12180) - 2452508..2454052 (-) 1545 WP_001830616.1 NAD(P)H-binding protein -

Sequence

Protein


Download         Length: 298 a.a.        Molecular weight: 34882.57 Da        Isoelectric Point: 7.2750

>NTDB_id=503661 HWI18_RS12270 WP_002437988.1 2448841..2449737(-) (braS) [Staphylococcus epidermidis strain UMCG345]
MKFAYIQSIRNEISIILIILLFFALIFYVFSLPFDAYVLAISIILLLMCVRWWIKYLSFKKNEHLKDKVAYLEHELAHVK
NQQIEYRNDVESYFLTWVHQIKTPITASQLLLERNEENVVNRVRQEIVHIDNYTSLALSYLKLLNEESDMTITKVTVDDL
IRPLLLKYRIQFIEQKTQIHYKKSEDIILTDAQWASIMIEQLLNNALKYAKGKDIWIDFDVANQTLQIKDNGIGISKADI
PKIFDKGYSGFNGRLNEQSTGIGLFIVQHIANHLNIQVTVQSELNHGTVFFIHFTKEK

Nucleotide


Download         Length: 897 bp        

>NTDB_id=503661 HWI18_RS12270 WP_002437988.1 2448841..2449737(-) (braS) [Staphylococcus epidermidis strain UMCG345]
ATGAAGTTTGCATATATTCAATCGATTCGTAATGAGATTTCAATTATTTTAATAATTCTATTATTTTTTGCACTTATATT
TTATGTGTTTTCTTTACCTTTTGATGCATACGTACTTGCAATCAGTATAATATTACTATTGATGTGTGTACGTTGGTGGA
TAAAGTATTTAAGTTTTAAAAAGAACGAACATCTTAAAGATAAAGTAGCATATTTAGAACATGAGTTAGCACATGTTAAG
AATCAGCAAATTGAATATCGTAACGATGTTGAAAGTTATTTTTTAACATGGGTACATCAAATTAAAACACCTATCACTGC
CTCACAATTACTTTTGGAGAGAAACGAGGAGAATGTAGTTAATCGTGTTAGACAAGAAATTGTGCACATTGATAATTATA
CAAGTCTCGCATTAAGTTATTTAAAATTATTAAATGAAGAGTCAGATATGACAATTACCAAAGTGACAGTTGATGATTTG
ATTCGCCCGTTGCTTTTAAAATATAGAATTCAGTTTATTGAGCAAAAGACGCAAATCCATTATAAAAAAAGTGAGGACAT
TATTTTAACCGATGCACAATGGGCGTCTATAATGATAGAGCAACTTTTAAATAATGCTTTAAAATATGCTAAAGGTAAAG
ATATTTGGATAGATTTTGATGTTGCCAATCAAACTCTACAGATTAAAGATAATGGTATTGGGATTAGTAAAGCAGATATT
CCTAAAATTTTTGATAAAGGATACTCAGGATTTAACGGTAGATTGAATGAACAATCAACTGGTATAGGTTTATTTATAGT
GCAACACATTGCAAATCATTTAAATATACAAGTAACTGTACAATCAGAATTGAATCATGGGACAGTATTTTTTATACATT
TTACTAAAGAAAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(197-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Q9W434

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braS Staphylococcus aureus N315

59.661

98.993

0.591