Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KQU62_RS08835 Genome accession   NZ_CP076660
Coordinates   1763711..1764427 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   P0A0I7
Organism   Staphylococcus aureus strain SG511 Berlin     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1758711..1769427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQU62_RS13555 (KQU62_08810) - 1759378..1759512 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  KQU62_RS08815 (KQU62_08815) - 1759748..1760311 (+) 564 WP_001105709.1 accessory gene regulator AgrB -
  KQU62_RS08820 (KQU62_08820) agrD 1760315..1760455 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  KQU62_RS13590 - 1760480..1760935 (+) 456 Protein_1712 sensor histidine kinase AgrC -
  KQU62_RS08825 (KQU62_08825) - 1761215..1762861 (+) 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
  KQU62_RS08830 (KQU62_08830) agrC 1762877..1763692 (+) 816 Protein_1714 quorum-sensing sensor histidine kinase AgrC -
  KQU62_RS08835 (KQU62_08835) agrA 1763711..1764427 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  KQU62_RS08840 (KQU62_08840) - 1764801..1765760 (-) 960 WP_216701788.1 carbohydrate kinase -
  KQU62_RS08845 (KQU62_08845) - 1765757..1767241 (-) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  KQU62_RS08850 (KQU62_08850) - 1767390..1768340 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=503595 KQU62_RS08835 WP_000688492.1 1763711..1764427(+) (agrA) [Staphylococcus aureus strain SG511 Berlin]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=503595 KQU62_RS08835 WP_000688492.1 1763711..1764427(+) (agrA) [Staphylococcus aureus strain SG511 Berlin]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3BS1
  PDB 4G4K

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1