Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   HWI21_RS00375 Genome accession   NZ_CP064609
Coordinates   78970..80331 (-) Length   453 a.a.
NCBI ID   WP_001631036.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain UMCG348     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 73970..85331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI21_RS00345 (HWI21_00345) - 74769..75179 (-) 411 WP_001631031.1 DUF2871 domain-containing protein -
  HWI21_RS00350 (HWI21_00350) - 75342..75562 (-) 221 Protein_67 hypothetical protein -
  HWI21_RS00355 (HWI21_00355) - 75577..76080 (-) 504 WP_001631032.1 DUF1643 domain-containing protein -
  HWI21_RS00360 (HWI21_00360) - 76096..76407 (-) 312 WP_001631033.1 DUF960 domain-containing protein -
  HWI21_RS00365 (HWI21_00365) - 76494..76844 (-) 351 WP_001631034.1 SAUGI family uracil-DNA glycosylase inhibitor -
  HWI21_RS00370 (HWI21_00370) ccrB 77345..78973 (-) 1629 WP_063964179.1 cassette chromosome recombinase CcrB Machinery gene
  HWI21_RS00375 (HWI21_00375) ccrA 78970..80331 (-) 1362 WP_001631036.1 cassette chromosome recombinase CcrA Machinery gene
  HWI21_RS00380 (HWI21_00380) - 80518..81147 (-) 630 Protein_73 hypothetical protein -
  HWI21_RS00385 (HWI21_00385) - 81156..81494 (+) 339 Protein_74 recombinase family protein -
  HWI21_RS00390 (HWI21_00390) - 81606..81965 (-) 360 WP_001631039.1 hypothetical protein -
  HWI21_RS00395 (HWI21_00395) - 82172..82498 (+) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -
  HWI21_RS00400 (HWI21_00400) - 82828..84753 (+) 1926 WP_002485723.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53316.45 Da        Isoelectric Point: 9.8596

>NTDB_id=503516 HWI21_RS00375 WP_001631036.1 78970..80331(-) (ccrA) [Staphylococcus epidermidis strain UMCG348]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=503516 HWI21_RS00375 WP_001631036.1 78970..80331(-) (ccrA) [Staphylococcus epidermidis strain UMCG348]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTTAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(168-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

54.628

97.792

0.534
  ccrA Staphylococcus aureus N315

50.564

97.792

0.494