Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HWI22_RS12270 Genome accession   NZ_CP064606
Coordinates   2444188..2444853 (-) Length   221 a.a.
NCBI ID   WP_001830679.1    Uniprot ID   A0A2G7HYS8
Organism   Staphylococcus epidermidis strain UMCG349     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2439188..2449853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI22_RS12250 (HWI22_12125) - 2439718..2440308 (-) 591 WP_001830621.1 DUF4064 domain-containing protein -
  HWI22_RS12255 (HWI22_12130) - 2440412..2442424 (-) 2013 WP_002456335.1 ABC transporter permease -
  HWI22_RS12260 (HWI22_12135) - 2442426..2443175 (-) 750 WP_001830627.1 ABC transporter ATP-binding protein -
  HWI22_RS12265 (HWI22_12140) braS 2443286..2444182 (-) 897 WP_002437988.1 HAMP domain-containing sensor histidine kinase Regulator
  HWI22_RS12270 (HWI22_12145) braR 2444188..2444853 (-) 666 WP_001830679.1 response regulator transcription factor Regulator
  HWI22_RS12275 (HWI22_12150) - 2444884..2445063 (-) 180 WP_001830653.1 hypothetical protein -
  HWI22_RS12280 (HWI22_12155) - 2445361..2446830 (+) 1470 WP_002484631.1 alkaline phosphatase -
  HWI22_RS12285 (HWI22_12160) - 2446953..2448497 (-) 1545 WP_001830616.1 NAD(P)H-binding protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25629.71 Da        Isoelectric Point: 5.0250

>NTDB_id=503510 HWI22_RS12270 WP_001830679.1 2444188..2444853(-) (braR) [Staphylococcus epidermidis strain UMCG349]
MKIFIVEDDLVIAESLANELSKWNYEVHVVDNFEKIMEDFRRVEPQLVLLDINLPTLNGFHWCQEMRKVSHVPIMFISSR
TDNMDQILAIQMGGDDFIEKPFNLSLTVAKIQALLRRTYDLSIARDEIAVKGCKLIVDEAKLSKDNEHVQLSLTELQILK
LLFQNENKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLLSIGVDDLIETKKNVGYRV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=503510 HWI22_RS12270 WP_001830679.1 2444188..2444853(-) (braR) [Staphylococcus epidermidis strain UMCG349]
ATGAAAATTTTCATTGTAGAAGACGATTTAGTGATTGCTGAAAGTTTAGCTAATGAGCTATCTAAATGGAATTATGAGGT
GCATGTGGTTGATAATTTTGAAAAGATAATGGAAGATTTTCGCCGAGTAGAACCACAACTCGTATTATTAGATATCAATC
TACCAACACTTAATGGCTTCCATTGGTGCCAAGAAATGCGAAAAGTATCTCATGTGCCTATTATGTTTATTAGTTCAAGA
ACAGATAATATGGATCAAATTCTGGCTATCCAAATGGGTGGCGATGATTTTATCGAGAAACCATTTAACTTGTCTTTAAC
AGTAGCTAAAATTCAGGCACTATTGCGTCGCACTTATGATTTATCAATAGCTCGTGATGAAATAGCTGTTAAAGGTTGTA
AACTAATTGTTGATGAGGCCAAGCTTAGCAAGGATAATGAACATGTTCAACTTTCCTTAACAGAGCTACAGATATTAAAA
TTGTTATTTCAAAATGAAAATAAATATGTAAGTCGTACAGCTTTAATTGAGAAGTGTTGGGAGTCTGAGAATTTTATTGA
TGACAATACGCTCGCAGTAAATATGACACGATTACGAAAAAAATTACTTTCTATCGGTGTCGATGATTTAATTGAGACAA
AGAAAAATGTAGGATATAGGGTTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2G7HYS8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

79.186

100

0.792