Detailed information NTG0503262

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI28_RS04390
• Genome accession: NZ_CP064580
• Coordinates: 945091..946137 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG355
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 940091..951137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI28_RS04365 (HWI28_04350)	isaB	941232..941768 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI28_RS04370 (HWI28_04355)	-	941919..942905 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI28_RS04375 (HWI28_04360)	map	943079..943834 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI28_RS04380 (HWI28_04365)	-	943992..944378 (+)	387	WP_001830382.1	hypothetical protein	-
HWI28_RS04385 (HWI28_04370)	liaF	944393..945094 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI28_RS04390 (HWI28_04375)	vraS	945091..946137 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI28_RS04395 (HWI28_04380)	vraR	946127..946756 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI28_RS04400 (HWI28_04385)	-	946813..947991 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI28_RS04405 (HWI28_04390)	-	948398..948682 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI28_RS04410 (HWI28_04395)	-	948690..949154 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI28_RS04415 (HWI28_04400)	-	949295..949510 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI28_RS04420 (HWI28_04405)	-	949512..950753 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=503262 HWI28_RS04390 WP_002486322.1 945091..946137(+) (vraS) [Staphylococcus epidermidis strain UMCG355]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=503262 HWI28_RS04390 WP_002486322.1 945091..946137(+) (vraS) [Staphylococcus epidermidis strain UMCG355]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917