Detailed information NTG0503110

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI33_RS04440
• Genome accession: NZ_CP064563
• Coordinates: 947651..948697 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG360
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 942651..953697

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI33_RS04415 (HWI33_04380)	isaB	943792..944328 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI33_RS04420 (HWI33_04385)	-	944479..945465 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI33_RS04425 (HWI33_04390)	map	945639..946394 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI33_RS04430 (HWI33_04395)	-	946552..946938 (+)	387	WP_001830382.1	hypothetical protein	-
HWI33_RS04435 (HWI33_04400)	liaF	946953..947654 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI33_RS04440 (HWI33_04405)	vraS	947651..948697 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI33_RS04445 (HWI33_04410)	vraR	948687..949316 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI33_RS04450 (HWI33_04415)	-	949373..950551 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI33_RS04455 (HWI33_04420)	-	950958..951242 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI33_RS04460 (HWI33_04425)	-	951250..951714 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI33_RS04465 (HWI33_04430)	-	951855..952070 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI33_RS04470 (HWI33_04435)	-	952072..953313 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=503110 HWI33_RS04440 WP_002486322.1 947651..948697(+) (vraS) [Staphylococcus epidermidis strain UMCG360]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=503110 HWI33_RS04440 WP_002486322.1 947651..948697(+) (vraS) [Staphylococcus epidermidis strain UMCG360]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917