Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   KPF76_RS02670 Genome accession   NZ_CP076509
Coordinates   536443..538257 (+) Length   604 a.a.
NCBI ID   WP_002783664.1    Uniprot ID   -
Organism   Campylobacter coli strain R18.1828     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 531443..543257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPF76_RS02650 (KPF76_02650) - 532838..533395 (+) 558 WP_052774371.1 class I SAM-dependent methyltransferase -
  KPF76_RS02655 (KPF76_02655) - 533518..534127 (-) 610 Protein_517 class I SAM-dependent DNA methyltransferase -
  KPF76_RS02660 (KPF76_02660) guaA 534302..535837 (-) 1536 WP_002777501.1 glutamine-hydrolyzing GMP synthase -
  KPF76_RS02665 (KPF76_02665) - 535974..536450 (+) 477 WP_002777499.1 hypothetical protein -
  KPF76_RS02670 (KPF76_02670) uvrC 536443..538257 (+) 1815 WP_002783664.1 excinuclease ABC subunit UvrC Machinery gene
  KPF76_RS02675 (KPF76_02675) - 538259..539452 (+) 1194 WP_002777493.1 hypothetical protein -
  KPF76_RS02680 (KPF76_02680) - 539449..540351 (-) 903 WP_002777490.1 radical SAM protein -
  KPF76_RS02685 (KPF76_02685) hemE 540348..541370 (-) 1023 WP_002789869.1 uroporphyrinogen decarboxylase -
  KPF76_RS02690 (KPF76_02690) - 541518..541829 (-) 312 WP_002777486.1 hypothetical protein -
  KPF76_RS02695 (KPF76_02695) - 542072..542677 (+) 606 WP_057030796.1 hypothetical protein -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 69737.71 Da        Isoelectric Point: 9.1921

>NTDB_id=502986 KPF76_RS02670 WP_002783664.1 536443..538257(+) (uvrC) [Campylobacter coli strain R18.1828]
MAEILLKNTLKEELQTLPANAGVYQYFNAEGKLLYVGKAKNLKNRVRSYFAFTPNLRANPKNSLRIQKMIEEAVHLEFIT
TNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFNEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYP
LKQKASCKSPCIFYQISRCLAPCDKKITQEEYRLILDKAINALLSPSILVKNLEKQMFHLAQNENYEEAAKIRDQIATIR
DLEIKVEIDIAKLEDFEIFALACESSMLSTLRFVVQNGKIISANSKITPLKNNTDFDKNEIYKQLILENFSVDIPLVANT
VYVYEDFEDRELLEEILSQRFDKKISIKVPKIGEKRRICDLAFQNACLNIQKEQKNSDFNIQKELKNYFELENLPNCIEV
FDNSHLQGVANVGAMITYKMGTWDKSNYRKFHLKYKNDYEQMREVLTRRALEFDKMPAPDLWLIDGGKALLDLAKEIILS
SGANVDILAISKEKINAKAHRAKGGAKDKIHSLKGEFALSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLSSSKLVK
SGLSAGVIQKLLAYYGSFEAIYEANFEELCQLVGKKSAQKIKED

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=502986 KPF76_RS02670 WP_002783664.1 536443..538257(+) (uvrC) [Campylobacter coli strain R18.1828]
ATGGCTGAAATTTTACTTAAAAATACTCTCAAAGAAGAGCTTCAAACCCTACCTGCAAATGCTGGAGTGTATCAGTATTT
TAATGCCGAAGGAAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAACCGCGTAAGATCTTATTTTGCTTTTACCC
CAAATTTACGCGCCAATCCAAAAAATTCTTTAAGAATTCAAAAAATGATAGAAGAAGCGGTGCATTTGGAATTTATTACA
ACAAATTCAGAAGCTGATGCTTTGATTTTGGAAAATTCTTTTATCAAGCAACTTCATCCAAAATACAATATTTTACTAAG
AGATGATAAGACTTATCCTTATATTTATGTAGATTTTAATGAAGAATTTCCGCGTTTTGAAATCACTAGAAAATTAGTTA
AAAAAAGTAAAATCAAATATTTTGGCCCCTTTTTTAAAGGAGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCT
TTAAAGCAAAAAGCAAGTTGTAAATCTCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAAAAAAT
TACCCAAGAAGAATATCGTTTGATTTTAGATAAAGCTATCAATGCTCTTTTAAGCCCTAGTATTTTAGTGAAAAATTTGG
AAAAACAAATGTTTCATTTAGCCCAAAATGAGAATTATGAAGAAGCGGCAAAAATAAGAGATCAGATTGCTACGATAAGG
GATTTGGAAATTAAAGTTGAGATTGATATCGCTAAATTAGAAGACTTTGAAATTTTTGCTTTAGCTTGTGAAAGCTCTAT
GCTTTCAACTTTGCGTTTTGTGGTGCAAAATGGAAAAATCATCAGCGCTAATTCTAAAATCACTCCGCTTAAAAACAATA
CAGATTTTGATAAAAATGAGATTTATAAACAGCTTATTTTAGAAAATTTTAGCGTAGACATTCCTTTGGTTGCAAATACT
GTTTATGTTTATGAGGATTTTGAAGACAGGGAGCTTTTAGAAGAAATTTTAAGCCAGAGATTTGATAAAAAAATCAGCAT
TAAAGTTCCTAAAATAGGGGAAAAAAGAAGAATTTGTGATTTGGCATTTCAAAATGCGTGTTTAAATATACAAAAAGAGC
AAAAAAATAGTGATTTTAATATACAAAAAGAACTTAAAAATTATTTCGAGCTTGAAAATCTGCCAAATTGTATAGAAGTT
TTTGATAATTCTCATTTGCAAGGTGTGGCGAATGTAGGAGCTATGATAACTTATAAAATGGGTACTTGGGATAAGTCAAA
TTATAGAAAATTTCATTTAAAATACAAAAATGATTATGAGCAAATGCGTGAAGTTTTAACGCGTAGAGCATTAGAATTTG
ACAAAATGCCTGCTCCTGATTTGTGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTAGCTAAAGAAATCATCTTAAGT
AGTGGGGCAAATGTTGATATTTTAGCAATCTCAAAAGAAAAAATCAATGCTAAAGCTCACCGCGCTAAAGGAGGGGCTAA
AGATAAAATTCACTCTTTAAAAGGAGAATTTGCCCTAAGCATTAACGATAAAAAATTACAATTCTTACAGAAATTAAGAG
ATGAAGCACATCGTTTTGCCATAAGTTTTCATCAAAACACTAAGAAAAAACAAGATTTATCAAGCTCTAAGCTTGTAAAA
TCAGGACTTAGTGCGGGAGTTATACAAAAACTTTTGGCGTATTATGGAAGTTTTGAAGCTATTTATGAGGCAAATTTTGA
AGAATTGTGCCAATTAGTAGGAAAAAAATCAGCACAAAAAATAAAGGAAGATTGA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(21-103)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(387-541)

UvrB/uvrC motif (UVR)

(209-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

46.01

97.517

0.449