Detailed information NTG0502962

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI37_RS04430
• Genome accession: NZ_CP064549
• Coordinates: 946310..947356 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG364
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 941310..952356

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI37_RS04405 (HWI37_04380)	isaB	942451..942987 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI37_RS04410 (HWI37_04385)	-	943138..944124 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI37_RS04415 (HWI37_04390)	map	944298..945053 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI37_RS04420 (HWI37_04395)	-	945211..945597 (+)	387	WP_001830382.1	hypothetical protein	-
HWI37_RS04425 (HWI37_04400)	liaF	945612..946313 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI37_RS04430 (HWI37_04405)	vraS	946310..947356 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI37_RS04435 (HWI37_04410)	vraR	947346..947975 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI37_RS04440 (HWI37_04415)	-	948032..949210 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI37_RS04445 (HWI37_04420)	-	949617..949901 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI37_RS04450 (HWI37_04425)	-	949909..950373 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI37_RS04455 (HWI37_04430)	-	950514..950729 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI37_RS04460 (HWI37_04435)	-	950731..951972 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=502962 HWI37_RS04430 WP_002486322.1 946310..947356(+) (vraS) [Staphylococcus epidermidis strain UMCG364]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=502962 HWI37_RS04430 WP_002486322.1 946310..947356(+) (vraS) [Staphylococcus epidermidis strain UMCG364]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917