Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   HWI38_RS13275 Genome accession   NZ_CP064545
Coordinates   2687390..2688736 (+) Length   448 a.a.
NCBI ID   WP_000816499.1    Uniprot ID   Q9R3W9
Organism   Staphylococcus epidermidis strain UMCG365     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2682390..2693736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI38_RS13250 (HWI38_13120) - 2682949..2683521 (-) 573 WP_000489177.1 ADP-ribosyltransferase -
  HWI38_RS13255 (HWI38_13125) - 2683574..2684623 (-) 1050 WP_000613217.1 hypothetical protein -
  HWI38_RS13260 (HWI38_13130) ssb 2684761..2685045 (+) 285 WP_000659554.1 cassette chromosome ssDNA-binding protein -
  HWI38_RS13265 (HWI38_13135) cch1 2685045..2686832 (+) 1788 WP_000181743.1 cassette chromosome replicative helicase -
  HWI38_RS13270 (HWI38_13140) - 2686922..2687197 (+) 276 WP_001791132.1 hypothetical protein -
  HWI38_RS13275 (HWI38_13145) ccrA 2687390..2688736 (+) 1347 WP_000816499.1 cassette chromosome recombinase CcrA Machinery gene
  HWI38_RS13280 (HWI38_13150) ccrB 2688757..2690385 (+) 1629 WP_001186596.1 cassette chromosome recombinase CcrB Machinery gene
  HWI38_RS13285 (HWI38_13155) - 2690856..2691206 (+) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  HWI38_RS13290 (HWI38_13160) - 2691291..2691602 (+) 312 WP_000833212.1 DUF960 family protein -
  HWI38_RS13295 (HWI38_13165) - 2691621..2692142 (+) 522 WP_000836008.1 DUF1643 domain-containing protein -
  HWI38_RS13300 (HWI38_13170) - 2692144..2692350 (+) 207 WP_001077283.1 hypothetical protein -
  HWI38_RS13305 (HWI38_13175) - 2692343..2692666 (+) 324 WP_000088091.1 JAB domain-containing protein -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 52138.19 Da        Isoelectric Point: 10.1760

>NTDB_id=502949 HWI38_RS13275 WP_000816499.1 2687390..2688736(+) (ccrA) [Staphylococcus epidermidis strain UMCG365]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=502949 HWI38_RS13275 WP_000816499.1 2687390..2688736(+) (ccrA) [Staphylococcus epidermidis strain UMCG365]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA

Domains

Predicted by InterProScan.

Recombinase (Recombinase)

(168-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

78.174

100

0.783
  ccrA Staphylococcus aureus N315

72.383

100

0.725